Evidence map›Paper›PMID 30740931›Full record

ArticleArthritis care & research2020

Three Quality Improvement Initiatives and Performance of Rheumatoid Arthritis Disease Activity Measures in Electronic Health Records: Results From an Interrupted Time Series Study.

Julie Gandrup, Jing Li, Zara Izadi, Milena Gianfrancesco, Torkell Ellingsen, Jinoos Yazdany, Gabriela Schmajuk

Open access · greenAbstract read
In one paragraph

Article in Arthritis care & research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Julie GandrupUniversity of California, San Francisco.
Jing LiUniversity of California, San Francisco.
Zara IzadiUniversity of California, San Francisco.ORCID 0000-0002-1867-0905
Milena GianfrancescoUniversity of California, San Francisco.ORCID 0000-0002-8351-4626
Torkell EllingsenOdense University Hospital, Odense, Denmark.
Jinoos YazdanyUniversity of California, San Francisco.
Gabriela SchmajukUniversity of California and the Veterans Affairs Medical Center, San Francisco.ORCID 0000-0003-2687-5043
University of California, San Francisco · USOdense University Hospital · DKSan Francisco VA Medical Center · US

Funding

RESOURCE-BASED CENTER FOR THE ADVANCEMENT OF PRECISION MEDICINE IN RHEUMATOLOGYP30AR070155 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Mary C Nakamura · 2016 to 2026
$8.2M
Advancing Quality and Outcomes Measurement in RheumatologyK24AR074534 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jinoos Yazdany · 2019 to 2026
$1.5M
Rheumatology Informatics System for Effectiveness Patient-Reported Outcome (RISE-PRO) Dissemination ProjectR18HS025638 · AHRQ · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YAZDANY, JINOOS · 2018 to 2020
$1.5M
A rational approach to liver toxicity monitoring in methotrexate usersK23AR063770 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SCHMAJUK, GABRIELA · 2013 to 2017
$670k
Evaluating Health Care Quality in Systemic Lupus ErythematosusK23AR060259 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YAZDANY, JINOOS · 2011 to 2015
$638k
Computational methods using electronic health records and registry data to detect and predict clinical outcomes in rheumatic diseaseK01AR075085 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GIANFRANCESCO, MILENA ANNE · 2019 to 2022
$458k
AHRQ HHS R18 HS025638LundbeckfondenNIAMS NIH HHS K01 AR075085NIAMS NIH HHS K23 AR060259NIAMS NIH HHS K23 AR063770NIAMS NIH HHS K24 AR074534NIAMS NIH HHS P30 AR070155PfizerRobert L. Kroc Chair in Rheumatic and Connective Tissue DiseasesRussell/Engleman Medical Research Center for Arthritis
6 · The paper itself

Abstract

objectiveApplying treat-to-target strategies in the care of patients with rheumatoid arthritis (RA) is critical for improving outcomes, yet electronic health records (EHRs) have few features to facilitate this goal. We undertook this study to evaluate the effect of 3 health information technology (health-IT) initiatives on the performance of RA disease activity measures and outcomes in an academic rheumatology clinic.

methodsWe implemented the 3 following initiatives designed to facilitate performance of the Clinical Disease Activity Index (CDAI): an EHR flowsheet to input scores, peer performance reports, and an EHR SmartForm including a CDAI calculator. We performed an interrupted time-series trial to assess effects on the proportion of RA visits with a documented CDAI. Mean CDAI scores before and after the last initiative were compared using t-tests. Additionally, we measured physician satisfaction with the initiatives.

resultsWe included data from 995 patients with 8,040 encounters between 2012 and 2017. Over this period, electronic capture of CDAI scores increased from 0% to 64%. Performance remained stable after peer reporting and the SmartForm were introduced. We observed no meaningful changes in disease activity levels. However, physician satisfaction increased after SmartForm implementation.

conclusionModifications to the EHR, provider culture, and clinical workflows effectively improved capture of RA disease activity scores and physician satisfaction, but parallel gains in disease activity levels were missing. This study illustrates how a series of health-IT initiatives can evolve to enable sustained changes in practice. However, capture of RA outcomes alone may not be sufficient to improve levels of disease activity without a comprehensive treat-to-target program.

Indexed as

Disease ProgressionAdultAgedArthritis, RheumatoidElectronic Health RecordsFemaleHealth PersonnelHumansInterrupted Time Series AnalysisMaleMiddle AgedQuality Improvement

Identifiers

PMID30740931
PMCPMC6689446
OpenAlexW2914827023

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.