Evidence map›Paper›PMID 30740582›Full record

ArticleIEEE transactions on radiation and plasma medical sciences2019

Advances in Computational Human Phantoms and Their Applications in Biomedical Engineering - A Topical Review.

Wolfgang Kainz, Esra Neufeld, Wesley E Bolch, Christian G Graff, Chan Hyeong Kim, Niels Kuster, Bryn Lloyd, Tina Morrison, Paul Segars, Yeon Soo Yeom and 3 more

Open access · greenAbstract read
In one paragraph

Article in IEEE transactions on radiation and plasma medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 104 citations in OpenAlex.

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  13. Nuclear Medicine and Artificial Intelligence: Best Practices for Evaluation (the RELAINCE Guidelines).Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
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  18. Roadmap: proton therapy physics and biology.Physics in medicine and biology · 2021
    Review
  19. Virtual Imaging Trials for Coronavirus Disease (COVID-19).AJR. American journal of roentgenology · 2021
    Article
  20. Comparison of Correction Techniques for the Spill in Effect in Emission Tomography.IEEE transactions on radiation and plasma medical sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 4 countries.

Wolfgang KainzFood and Drug Administration (FDA), Center for Devices and Radiological Health (CDRH), Silver Spring, MD 20993 USA (wolfgang.kainz@fda.hhs.gov).
Esra NeufeldFoundation for Research on Information Technologies in Society (IT'IS), Zurich, Switzerland (neufeld@itis.ethz.ch).
Wesley E BolchUniversity of Florida, Gainesville, FL, USA (wbolch@ufl.edu).
Christian G GraffFood and Drug Administration (FDA), Center for Devices and Radiological Health (CDRH), Silver Spring, MD 20993 USA (christian.graff@fda.hhs.gov).
Chan Hyeong KimHanyang University, Seoul, South Korea (chkim@hanyang.ac.kr).
Niels KusterSwiss Federal Institute of Technology, ETH Zürich, and the Foundation for Research on Information Technologies in Society (IT'IS), Zürich, Switzerland (kuster@itis.ethz.ch).
Bryn LloydFoundation for Research on Information Technologies in Society (IT'IS), Zurich, Switzerland (lloyd@itis.ethz.ch).
Tina MorrisonFood and Drug Administration (FDA), Center for Devices and Radiological Health (CDRH), Silver Spring, MD 20993 USA (tina.morrison@fda.hhs.gov).
Paul SegarsDuke University, Durham, NC, USA (paul.segars@duke.edu).
Yeon Soo YeomNational Institutes of Health (NIH), MD, USA (yeonsoo.yeom@nih.gov).
Maria ZanklHelmholtz Zentrum München German Research Center for Environmental Health, Munich, Germany (zankl@helmholtz-muenchen.de).
X George XuRensselaer Polytechnic Institute, Troy, NY, USA (xug2@rpi.edu).
Benjamin M W TsuiJohns Hopkins University, School of Medicine, Baltimore, MD, USA (btsui@jhmi.edu).
Center for Devices and Radiological Health · USFoundation for Research on Information Technologies in Society · CHDuke University · USHanyang University · KRHelmholtz Zentrum München · DEJohns Hopkins University · USNational Institutes of Health · USRensselaer Polytechnic Institute · USUniversity of Florida · US

Funding

Simulation Tools for Dynamic CTR01EB001838 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI SAMEI, EHSAN, SEGARS, WILLIAM P · 2005 to 2023
$6.9M
Precision Cardiac CT: Development of a Computational Platform for Optimizing ImagingR01HL131753 · NHLBI · DUKE UNIVERSITY · PI SAMEI, EHSAN, SEGARS, WILLIAM P · 2017 to 2020
$2.7M
Intramural FDA HHS FD999999NHLBI NIH HHS R01 HL131753NIBIB NIH HHS R01 EB001838
6 · The paper itself

Abstract

Over the past decades, significant improvements have been made in the field of computational human phantoms (CHPs) and their applications in biomedical engineering. Their sophistication has dramatically increased. The very first CHPs were composed of simple geometric volumes, e.g., cylinders and spheres, while current CHPs have a high resolution, cover a substantial range of the patient population, have high anatomical accuracy, are poseable, morphable, and are augmented with various details to perform functionalized computations. Advances in imaging techniques and semi-automated segmentation tools allow fast and personalized development of CHPs. These advances open the door to quickly develop personalized CHPs, inherently including the disease of the patient. Because many of these CHPs are increasingly providing data for regulatory submissions of various medical devices, the validity, anatomical accuracy, and availability to cover the entire patient population is of utmost importance. The article is organized into two main sections: the first section reviews the different modeling techniques used to create CHPs, whereas the second section discusses various applications of CHPs in biomedical engineering. Each topic gives an overview, a brief history, recent developments, and an outlook into the future.

Indexed as

computational modelingHuman anatomyphantoms

Identifiers

PMID30740582
PMCPMC6362464
OpenAlexW2903213872

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.