ArticleThe Russell Sage Foundation journal of the social sciences : RSF2018
Geographic Clustering of Polygenic Scores at Different Stages of the Life Course.
Article in The Russell Sage Foundation journal of the social sciences : RSF, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Rare genetic variants explain missing heritability in smoking.Nature human behaviour · 2022Article
- Resource profile and user guide of the Polygenic Index Repository.Nature human behaviour · 2021Article
- Evaluating the Continued Integration of Genetics into Medical Sociology.Journal of health and social behavior · 2021Article
- Cognition in context: Pathways and compound risk in a sample of US non-Hispanic whites.Social science & medicine (1982) · 2021Article
- Genetic correlates of social stratification in Great Britain.Nature human behaviour · 2019Article
- Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis.Nature communications · 2019Article
- Schools as Moderators of Genetic Associations with Life Course Attainments: Evidence from the WLS and Add Health.Sociological science · 2018Article
- The social genome of friends and schoolmates in the National Longitudinal Study of Adolescent to Adult Health.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
We interrogate state-level clustering of polygenic scores at different points in the life course and variation in the association of mean polygenic scores in a respondent's state of birth with corresponding phenotypes. The polygenic scores for height and smoking show the most state-level clustering (2 to 4 percent) with relatively little clustering observed for the other scores. However, even the small amounts of observed clustering are potentially meaningful. The state-mean polygenic score for educational attainment is strongly associated with an individual's educational attainment net of that person's polygenic score. The ecological clustering of polygenic scores may denote a new environmental factor in gene-environment research. We conclude by discussing possible mechanisms that underlie this association and the implications of our findings for social and genetic research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.