Evidence map›Paper›PMID 30740462›Full record

ArticleERJ open research2019

Indoor air pollution and tobacco smoke exposure: impact on nasopharyngeal bacterial carriage in mothers and infants in an African birth cohort study.

Aneesa Vanker, Polite M Nduru, Whitney Barnett, Felix S Dube, Peter D Sly, Robert P Gie, Mark P Nicol, Heather J Zar

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ERJ open research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. The association between bacteria colonizing the upper respiratory tract and lower respiratory tract infection in young children: a systematic review and meta-analysis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2021
    Pooled it
  3. Article
  4. Air Pollution and Global Pediatric Pneumococcal Disease.Open forum infectious diseases · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Article
  18. Lung Health in Children in Sub-Saharan Africa: Addressing the Need for Cleaner Air.International journal of environmental research and public health · 2020
    Review
  19. Magnitude ofRisk management and healthcare policy · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Aneesa VankerDept of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, and SAMRC Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa.
Polite M NduruDept of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, and SAMRC Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa.
Whitney BarnettDept of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, and SAMRC Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa.
Felix S DubeDept of Molecular and Cell Biology, Faculty of Science, University of Cape Town, Cape Town, South Africa.
Peter D SlyChildren's Health and Environment Program, Child Health Research Centre, The University of Queensland, South Brisbane, Australia.
Robert P GieDept of Paediatrics and Child Health, Tygerberg Children's Hospital, Stellenbosch University, Cape Town, South Africa.
Mark P NicolDivision of Medical Microbiology, Dept of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Heather J ZarDept of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, and SAMRC Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa.
University of Cape Town · ZARed Cross War Memorial Children's Hospital · ZANational Health Laboratory Service · ZAStellenbosch University · ZAUniversity of Queensland · AU

Funding

The nasopharyngeal microbiota of African children and lower respiratory tract infectionU54HG009824 · NHGRI · UNIVERSITY OF CAPE TOWN · PI NICOL, MARK PATRICK · 2017 to 2021
$2.9M
The nasopharyngeal microbiome and respiratory disease in African childrenU01AI110466 · NIAID · UNIVERSITY OF CAPE TOWN · PI NICOL, MARK PATRICK, ZAR, HEATHER JOY · 2013 to 2016
$1.4M
NHGRI NIH HHS U54 HG009824NIAID NIH HHS U01 AI110466
6 · The paper itself

Abstract

Indoor air pollution (IAP) or environmental tobacco smoke (ETS) exposure may influence nasopharyngeal carriage of bacterial species and development of lower respiratory tract infection (LRTI). The aim of this study was to longitudinally investigate the impact of antenatal or postnatal IAP/ETS exposure on nasopharyngeal bacteria in mothers and infants. A South African cohort study followed mother-infant pairs from birth through the first year. Nasopharyngeal swabs were taken at birth, 6 and 12 months for bacterial culture. Multivariable and multivariate Poisson regression investigated associations between nasopharyngeal bacterial species and IAP/ETS. IAP exposures (particulate matter, carbon monoxide, nitrogen dioxide, volatile organic compounds) were measured at home visits. ETS exposure was measured through maternal and infant urine cotinine. Infants received the 13-valent pneumococcal and

Identifiers

PMID30740462
PMCPMC6360211
OpenAlexW2912232682

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.