Evidence map›Paper›PMID 30740241›Full record

ArticleRegenerative biomaterials2019

A portable device for studying the effects of fluid flow on degradation properties of biomaterials inside cell incubators.

Wensen Jiang, Jiajia Lin, Alex H Chen, Jianwei Pan, Huinan Liu

Open access · goldAbstract read
In one paragraph

Article in Regenerative biomaterials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. CaCOFrontiers in nutrition · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Wensen JiangDepartment of Bioengineering, Materials Science and Engineering Program, Stem Cell Center.
Jiajia LinDepartment of Bioengineering, Materials Science and Engineering Program, Stem Cell Center.
Alex H ChenDepartment of Mechanical Engineering, University of California, Riverside, Riverside, CA, USA.
Jianwei PanDepartment of Neurosurgery, The First Affiliated Hospital of Zhejiang University, Hangzhou, China.
Huinan LiuDepartment of Bioengineering, Materials Science and Engineering Program, Stem Cell Center.
University of California, Riverside · USFirst Affiliated Hospital Zhejiang University · CN

Funding

American Heart Association-American Stroke Association 12SDG12220014
6 · The paper itself

Abstract

A portable device was designed and constructed for studying the properties of biomaterials in physiologically relevant fluids under controllable flow conditions that closely simulate fluid flow inside the body. The device can fit entirely inside a cell incubator; and, thus, it can be used directly under standard cell culture conditions. An impedance-driven pump was built in the sterile flow loop to control the flow rates of fluids, which made the device small and portable for easy deployment in the incubator. To demonstrate the device functions, magnesium (Mg) as a representative biodegradable material was tested in the flow device for immersion degradation under flow versus static conditions, while the flow module was placed inside a standard cell incubator. The flow rate was controlled at 0.17 ± 0.06 ml/s for this study; and, the flow rate is adjustable through the controller module outside of incubators for simulating the flow rates in the ranges of blood flow in human artery (0.05 ∼0.43 ml/s) and vein (0.02 ∼0.08 ml/s). Degradation of Mg under flow versus static conditions was characterized by measuring the changes of sample mass and thickness, and Mg

Indexed as

biomaterialsbody fluidsimpedance-driven pumpmagnesium (Mg) degradationportable flow device

Identifiers

PMID30740241
PMCPMC6362820
OpenAlexW2905643996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.