Evidence map›Paper›PMID 30740152›Full record

ArticleOpen access Macedonian journal of medical sciences2019

Vancomycin MIC Distribution among Methicillin-Resistant

Hala B Othman, Rania M Abdel Halim, Fatma Alzahraa M Gomaa, Malaka Z Amer

Abstract read
In one paragraph

Article in Open access Macedonian journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Antihemolytic and Thrombolytic Potential ofJournal of tropical medicine · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hala B OthmanClinical Pathology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Rania M Abdel HalimClinical Pathology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Fatma Alzahraa M GomaaMicrobiology and Immunology Department, Faculty of Pharmacy, Al Azhar University, Cairo, Egypt.
Malaka Z AmerClinical Pathology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo determine the distribution of vancomycin MIC and the frequency of

methodsMRSA isolates (n = 100) were tested for reduced susceptibility to vancomycin using MIC broth microdilution method (BMD), vancomycin screening agar with different vancomycin concentrations with and without casein, and Vitek 2 system.

resultsBMD detected (22%) vancomycin-intermediate

conclusionVancomycin screening agar; 2 µg/ml and (4 and 6 µg/ml) were able to detect; probable "pre hVISA and (hVISA and VISA) isolates respectively based on their BMD MIC values. Decreased vancomycin susceptibility in MRSA isolates might be related to MIC creep. Analysis of vancomycin MIC values over longer periods is recommended to further study this phenomenon and its impact on vancomycin treatment failure.

Indexed as

BMDh-VISAVancomycin MIC creepVancomycin screening agarVISA

Identifiers

PMID30740152
PMCPMC6352480

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.