Evidence map›Paper›PMID 30740107›Full record

ArticleFrontiers in immunology2019

A Syrian Refugee in Iraq Diagnosed as a Case of IL12RB1 Deficiency in Japan Using Dried Blood Spots.

Lika'a Fasih Y Al-Kzayer, Ahmed K Yassin, Khalid Hama Salih, Tomonari Shigemura, Kenji Sano, Ruwaid Behnam Y Al-Simaani, Miyuki Tanaka, Yozo Nakazawa, Yusuke Okuno

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Pulmonary non-tuberculous mycobacterial infections: current state and future management.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Lika'a Fasih Y Al-KzayerDepartment of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.
Ahmed K YassinDepartment of Medicine, College of Medicine, Hawler Medical University, Erbil, Iraq.
Khalid Hama SalihDepartment of Pediatrics, College of Medicine, Sulaymaniyah Medical University, Sulaymaniyah, Iraq.
Tomonari ShigemuraDepartment of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.
Kenji SanoDepartment of Pathology, Iida Municipal Hospital, Iida, Japan.
Ruwaid Behnam Y Al-SimaaniDepartment of Pediatrics, Noorjan Medical Complex, Erbil, Iraq.
Miyuki TanakaDepartment of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.
Yozo NakazawaDepartment of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.
Yusuke OkunoCenter for Advanced Medicine and Clinical Research, Nagoya University Hospital, Nagoya, Japan.
Shinshu University · JPHawler Medical University · IQIkeda Municipal Hospital · JPNagoya University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mendelian susceptibility to mycobacterial diseases (MSMD) is a rare condition of primary immunodeficiency disorder. Interleukin-12 receptor β1 (IL12RB1) deficiency, is the most common genetic etiology of MSMD, which is characterized by the selective predisposition to clinical disease caused by weakly-virulent mycobacteria, such as Bacillus Calmette-Guérin (BCG) vaccines, and environmental non-tuberculous mycobacteria (NTM). To the best of our knowledge, this is the first case of

Indexed as

Dried Blood Spot TestingRefugeesAnti-Bacterial AgentsBCG VaccineChildConsanguinityDiagnosis, DifferentialExome SequencingFemaleGenetic Predisposition to DiseaseHumansImmunologic Deficiency SyndromesIraqJapanMutationMycobacterium Infections, NontuberculousAnti-Bacterial AgentsBCG VaccineIL12RB1 protein, humanReceptors, Interleukin-12Bacillus Calmette-Guérin (BCG)Flinders Technology Associates (FTA)IL12RB1 deficiencyIraqmendelian susceptibility to mycobacterial diseases (MSMD)non-tuberculous mycobacteria (NTM)tuberculosis (TB)whole exome sequencing (WES)

Identifiers

PMID30740107
PMCPMC6355664
OpenAlexW2911759300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.