Evidence map›Paper›PMID 30740100›Full record

ArticleFrontiers in immunology2019

Ankylosing Spondylitis: A Trade Off of HLA-B27, ERAP, and Pathogen Interconnections? Focus on Sardinia.

Fabiana Paladini, Maria Teresa Fiorillo, Valentina Tedeschi, Alberto Cauli, Alessandro Mathieu, Rosa Sorrentino

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Role of the Hemostasis and Thrombosis Unit in the Management of Patients with Acquired Hemophilia ATurkish journal of haematology : official journal of Turkish Society of Haematology · 2024
    Article
  6. The Role of Aminopeptidase ERAP1 in Human Pathology-A Review.Current issues in molecular biology · 2024
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Fabiana PaladiniDepartment of Biology and Biotechnology "Charles Darwin", Sapienza University, Rome, Italy.
Maria Teresa FiorilloDepartment of Biology and Biotechnology "Charles Darwin", Sapienza University, Rome, Italy.
Valentina TedeschiDepartment of Biology and Biotechnology "Charles Darwin", Sapienza University, Rome, Italy.
Alberto CauliDepartment of Medical Sciences and Public Health, Chair of Rheumatology and Rheumatology Unit, University and AOU of Cagliari, Cagliari, Italy.
Alessandro MathieuDepartment of Medical Sciences and Public Health, Chair of Rheumatology and Rheumatology Unit, University and AOU of Cagliari, Cagliari, Italy.
Rosa SorrentinoDepartment of Biology and Biotechnology "Charles Darwin", Sapienza University, Rome, Italy.
University of Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The frequency of HLA-B27 in patients with Ankylosing Spondylitis (AS) is over 85%. There are more than 170 recognized HLA-B27 alleles but the majority of them is not sufficiently represented for genetic association studies. So far only two alleles, the HLA-B

Indexed as

Polymorphism, Single NucleotideAllelesAminopeptidasesAntigen PresentationCystinyl AminopeptidaseEndemic DiseasesGene FrequencyHaplotypesHLA-B27 AntigenHumansItalyMalariaMinor Histocompatibility AntigensSpondylitis, AnkylosingAminopeptidasesCystinyl AminopeptidaseERAP1 protein, humanERAP2 protein, humanHLA-B*27:06 antigenHLA-B*27:09 antigenHLA-B27 Antigenleucyl-cystinyl aminopeptidaseMinor Histocompatibility Antigensankylosing spondylitisautoimmunityERAP1 and 2HLA-B27 allelesmalaria

Identifiers

PMID30740100
PMCPMC6355666
OpenAlexW2912269716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.