ReviewFrontiers in neurology2019
Timing of Decompressive Craniectomy for Ischemic Stroke and Traumatic Brain Injury: A Review.
Review in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- Does erythropoietin affect the outcome and complication rates of patient with traumatic brain injury? A pooled-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Pooled it
- The prevalence and risk factors of posttraumatic cerebral infarction in patients with traumatic brain injury: a systematic review and meta-analysis.Bioengineered · 2022Pooled it
- A systematic review of mortality and long-term functional outcomes after decompressive craniectomy for acquired brain injury: The missing rehabilitation reporting.AIMS neuroscience · 2026Review
- Outcome of Ischemic Stroke Patients Following Decompressive Craniectomy: A Cohort Study.Iranian journal of medical sciences · 2025Article
- Article
- Caring for Coma after Severe Brain Injury: Clinical Practices and Challenges to Improve Outcomes: An Initiative by the Curing Coma Campaign.Neurocritical care · 2025Article
- Decompressive Craniectomy and Hinged Craniotomy for Traumatic Brain Injury: Experience in Two Centers in a Middle-Income Country.Korean journal of neurotrauma · 2024Article
- Basic study on cryopreservation of rat calvarial osteoblasts with different cryoprotectants.Cell and tissue banking · 2024Article
- Review
- Single-centre real-life observational study on mortality and outcomes: decompressive craniectomy and brain death in traumatic brain injury, haemorrhage, and other cerebral diseases.Acta neurochirurgica · 2024Observational
- Current state of neuroprotective therapy using antibiotics in human traumatic brain injury and animal models.BMC neuroscience · 2024Review
- Role of decompressive craniectomy in the management of acute ischemic stroke (Review).Biomedical reports · 2024Review
- Outcome after decompressive craniectomy in older adults after traumatic brain injury.Frontiers in medicine · 2024Article
- Use of biomarkers for predicting a malignant course in acute ischemic stroke: an observational case-control study.Scientific reports · 2023Observational
- Prediction of Increased Intracranial Pressure in Traumatic Brain Injury Using Quantitative Electroencephalogram in a Porcine Experimental Model.Diagnostics (Basel, Switzerland) · 2023Article
- Effect of cranioplasty on FIM in patients with severe cerebral infarction after cerebral decompression.Japanese journal of comprehensive rehabilitation science · 2023Article
- Impact of COVID-19 on neurocritical care delivery and outcomes in patients with severe acute brain injury - Assessing the initial response in the first US epicenter.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2022Article
- Outcome of Decompressive Craniectomy for Traumatic Brain Injury: Ways to Better Evaluate Functional Outcome.Asian journal of neurosurgery · 2022Article
- Severe Traumatic Brain Injury in children-paradigm of decompressive craniectomy compared to a historic cohort.Acta neurochirurgica · 2022Article
- Excavating FAIR Data: the Case of the Multicenter Animal Spinal Cord Injury Study (MASCIS), Blood Pressure, and Neuro-Recovery.Neuroinformatics · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While studies have demonstrated that decompressive craniectomy after stroke or TBI improves mortality, there is much controversy regarding when decompressive craniectomy is optimally performed. The goal of this paper is to synthesize the data regarding timing of craniectomy for malignant stroke and traumatic brain injury (TBI) based on studied time windows and clinical correlates of herniation. In stroke patients, evidence supports that early decompression performed within 24 h or before clinical signs of herniation may improve overall mortality and functional outcomes. In adult TBI patients, published results demonstrate that early decompressive craniectomy within 24 h of injury may reduce mortality and improve functional outcomes when compared to late decompressive craniectomy. In contrast to the stroke data, preliminary TBI data have demonstrated that decompressive craniectomy after radiographic signs of herniation may still lead to improved functional outcomes compared to medical management. In pediatric TBI patients, there is also evidence for better functional outcomes when treated with decompressive craniectomy, regardless of timing. More high quality data are needed, particularly that which incorporates a broader set of metrics into decision-making surrounding cranial decompression. In particular, advanced neuromonitoring and imaging technologies may be useful adjuncts in determining the optimal time for decompression in appropriate patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.