Evidence map›Paper›PMID 30739385›Full record

ArticleTropical medicine & international health : TM & IH2019

Changes in disclosure, adherence and healthcare interactions after the introduction of immediate ART initiation: an analysis of patient experiences in Swaziland.

Marjan Molemans, Eva Vernooij, Njabuliso Dlamini, Fortunate S Shabalala, Shaukat Khan, Frank van Leth, Gabriela B Gomez, Ria Reis

Open access · hybridAbstract readControlled Clinical Trial
In one paragraph

Article in Tropical medicine & international health : TM & IH, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 5 countries.

Marjan MolemansDepartment of Global Health, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Eva VernooijAmsterdam Institute for Social Science Research, Department of Anthropology, University of Amsterdam, Amsterdam, The Netherlands.
Njabuliso DlaminiAmsterdam Institute for Social Science Research, Department of Anthropology, University of Amsterdam, Amsterdam, The Netherlands.
Fortunate S ShabalalaAmsterdam Institute for Social Science Research, Department of Anthropology, University of Amsterdam, Amsterdam, The Netherlands.
Shaukat KhanClinton Health Access Initiative, Mbabane, Swaziland.
Frank van LethDepartment of Global Health, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Gabriela B GomezAmsterdam Institute for Global Health and Development, Amsterdam, The Netherlands.
Ria ReisAmsterdam Institute for Global Health and Development, Amsterdam, The Netherlands.
Amsterdam Institute for Global Health and Development · NLAmsterdam University of Applied Sciences · NLAcademic Medical Center · NLAmsterdam Institute for Addiction Research · NLClinton Health Access Initiative · USInternational Institute of Social History · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere are concerns that immediate ART initiation (regardless of CD4 count) negatively affects HIV status disclosure, ART adherence and healthcare interactions. We assessed changes in these factors after the 'Early access to ART for all' intervention, a universal test-and-treat study in Swaziland.

methodsWe recruited two samples of participants between 2014 and 2017. The first group was interviewed before the intervention (control); the second group at the implementation and 6 months thereafter (intervention).

resultsHigh levels of disclosure to partners (controls and intervention: 94%) and family members (controls: 78%, intervention: 79%) were reported, and high levels of adherence (85% did not miss a dose among the controls, 84% in the intervention group). There were no changes in patients reporting feeling pressured to initiate ART (controls: 10%, intervention: 11%). The quality of interaction with healthcare workers improved after the intervention; healthcare workers explained more often the choice of ART initiation (controls: 88%, intervention: 93%) and the meaning of both CD4 and viral load test results (controls: 15%, intervention: 47%). More patients in the intervention group reported receiving test results (controls: 13%, intervention: 46%). We observed no changes in disclosure, adherence or patient experiences 6 months into the intervention compared to its start.

conclusionOur results suggest that both reported adherence and disclosure levels remain high after the introduction of immediate ART in Swaziland. We observed an improvement in the healthcare interactions, possibly due to training at participating facilities, which will be an important element for a successful roll-out of immediate ART.

Indexed as

CD4 Lymphocyte CountDisclosureFamilyMedication AdherenceSexual PartnersAdultAnti-HIV AgentsEswatiniFemaleHealth PersonnelHealth Services AccessibilityHealth StatusHIV InfectionsHumansMaleMiddle AgedAnti-HIV Agentsadherenceadhésionantiretroviral therapyARTdisclosuredivulgationHIVSwazilandtraitement préventiftreatment as preventionVIH

Identifiers

PMID30739385
PMCPMC6850272
OpenAlexW2912630642

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.