Evidence map›Paper›PMID 30739288›Full record

Trial reportQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2019

Effects of a simple home exercise program and vitamin D supplementation on health-related quality of life after a hip fracture: a randomized controlled trial.

K Renerts, K Fischer, B Dawson-Hughes, E J Orav, G Freystaetter, H-P Simmen, H-C Pape, A Egli, R Theiler, H A Bischoff-Ferrari

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Interventions for improving mobility after hip fracture surgery in adults.The Cochrane database of systematic reviews · 2022
    Pooled it
  2. Trial
  3. Health-related quality of life after hip fracture: effects of a 12-month home-based exercise intervention-secondary analyses of an RCT.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Trial
  4. Trial
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

K Renerts *Department of Geriatrics and Aging Research, University Hospital Zurich and University of Zurich, RAE B1, Rämistrasse 100, 8091, Zurich, Switzerland.ORCID http://orcid.org/0000-0001-5772-7014
K Fischer *Department of Geriatrics and Aging Research, University Hospital Zurich and University of Zurich, RAE B1, Rämistrasse 100, 8091, Zurich, Switzerland.
B Dawson-HughesJean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA.
E J OravJean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA.
G FreystaetterDepartment of Geriatrics and Aging Research, University Hospital Zurich and University of Zurich, RAE B1, Rämistrasse 100, 8091, Zurich, Switzerland.
H-P SimmenCentre for Senior Trauma Care, University Hospital Zurich, Zurich, Switzerland.
H-C PapeCentre for Senior Trauma Care, University Hospital Zurich, Zurich, Switzerland.
A EgliDepartment of Geriatrics and Aging Research, University Hospital Zurich and University of Zurich, RAE B1, Rämistrasse 100, 8091, Zurich, Switzerland.
R TheilerDepartment of Geriatrics and Aging Research, University Hospital Zurich and University of Zurich, RAE B1, Rämistrasse 100, 8091, Zurich, Switzerland.
H A Bischoff-FerrariDepartment of Geriatrics and Aging Research, University Hospital Zurich and University of Zurich, RAE B1, Rämistrasse 100, 8091, Zurich, Switzerland. Heike.Bischoff@usz.ch.

Funding

Swiss National Foundations Professorship Grant PP00B- 114864Universität Zürich University Research Priority Program ,,Dynamics of Healthy Aging"
6 · The paper itself

Abstract

purposeTo test the effects of vitamin D intervention and a simple home exercise program (HE) on health-related quality of life (HRQL) in the first 12 months after hip fracture.

methodsHRQL was reported in 173 acute hip fracture patients (mean age 84 years, 79% females, 77% community dwelling) who were enrolled in the 12-month 2 × 2 factorial Zurich Hip Fracture Trial. Pre-fracture HRQL was assessed at baseline (4.2 ± 2.2 days post-surgery) and then again at 6 and 12 months after hip fracture surgery by the EuroQol EQ-5D-3L index value (EQ-5D-3L questionnaire). The effects of vitamin D intervention (2000 vs. 800 IU vitamin D

resultsThe EQ-5D-3L index value significantly worsened from 0.71 pre-fracture to 0.57 over 12 months, but the degree of worsening did not differ between individual or combined interventions. However, regarding only the late recovery between 6 and 12 months, the group receiving neither intervention (800 IU/day and no HE) experienced a significant further decline in the EQ-5D-3L index value (adjusted mean change = 0.08 [95% CI 0.009, 0.15], p = 0.03) while all other groups remained stable.

conclusionHip fractures have a long-lasting negative effect on HRQL up to 12 months after hip fracture. However, HE and/or 2000 IU vitamin D per day may help prevent a further decline in HRQL after the first 6 months following the acute hip fracture event.

Indexed as

Dietary SupplementsAgedAged, 80 and overExercise TherapyFemaleHip FracturesHumansMaleQuality of LifeSurveys and QuestionnairesVitamin DVitamin DElderlyExerciseHip fractureQuality of lifeRCTVitamin D

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.