ArticleFolia microbiologica2019
Probiotic characteristics of bacteriocin-producing Enterococcus faecium strains isolated from human milk and colostrum.
Article in Folia microbiologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 53 citations in OpenAlex.
- Review
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- Comparison and correlation analysis of microbiota composition and short-chain fatty acid profile in Milk across 15 mammalian species.Food chemistry: X · 2025Article
- Functional efficacy ofFuture microbiology · 2025Article
- The Enterococcus secretome inhibits the growth of vancomycin-resistant Enterococcus faecalis V853 with their antiproliferative properties and nanoencapsulation effects.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Fermentation of Whole-Wheat Using Different Combinations of Lactic Acid Bacteria and Yeast: Impact on In Vitro and Ex Vivo Antioxidant Activity.Foods (Basel, Switzerland) · 2025Article
- The alleviating effects and mechanisms ofFrontiers in veterinary science · 2025Article
- Whole-genome sequencing ofMicrobiology resource announcements · 2024Article
- Microbiological risk assessment and resistome analysis from shotgun metagenomics of bovine colostrum microbiome.Saudi journal of biological sciences · 2024Article
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- Intestinal Dysbiosis in Rats: Interaction between Amoxicillin and Probiotics, a Histological and Immunohistochemical Evaluation.Nutrients · 2023Article
- Effect of Gastrointestinal Digestion on the Bioaccessibility of Phenolic Compounds and Antioxidant Activity of FermentedAntioxidants (Basel, Switzerland) · 2022Article
- Screening and identification of lactic acid bacteria with antimicrobial abilities for aquaculture pathogens in vitro.Archives of microbiology · 2022Article
- Evolution and antimicrobial resistance of enterococci isolated from Pecorino and goat cheese manufactured on-farm in an area facing constraints as per EU Regulation 1305/2013 in Umbria, Italy.Italian journal of food safety · 2022Article
- Potential ProbioticFoods (Basel, Switzerland) · 2021Article
- Stimulation of Bovicin HC5 Production and Selection of Improved Bacteriocin-Producing Streptococcus equinus HC5 Variants.Probiotics and antimicrobial proteins · 2021Article
- Anti-Proliferative and Anti-Biofilm Potentials of Bacteriocins Produced by Non-Pathogenic Enterococcus sp.Probiotics and antimicrobial proteins · 2021Article
- Article
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
As potential probiotic traits of human milk-isolated bacteria have increasingly been recognized, this study aimed to evaluate the probiotic properties of bacteriocin-producing Enterococcus faecium strains isolated from human milk and colostrum. Among 118 human milk- and colostrum-isolated lactic cocci, only 29 were identified as Enterococcus. Of these, only four Enterococcus faecium isolates exhibited bacteriocigenic activity against several pathogenic Gram-positive bacteria, including Listeria monocytogenes. These isolates exhibited high acid (up to pH 3.0) and bile tolerance (0.5% oxgall) in simulated gastrointestinal conditions, demonstrating their ability to survive through the upper gastrointestinal tract. All of the E. faecium strains were shown to be sensitive to most of the antibiotics including vancomycin, tetracycline, rifampicin, and erythromycin, while they were resistant to kanamycin and chloramphenicol. None of the strains showed any virulence (gelE, agg2, clyA, clyB, clyM) and antibiotic resistance genes (vanA, vanB, ermB, tetM, and aac(6')-le-aph(2″)-la). In addition, all the strains were able to assimilate cholesterol, ranging between 25.2-64.1% and they exhibited variable adherence (19-36%) to Caco-2 cells. Based on the overall results of this in vitro study, four of the E. faecium strains isolated from human milk and colostrum can be considered as promising probiotic candidates; however, further in vivo evaluations are required.
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