ArticleMikrochimica acta2019
Nitrogen-doped carbon nanodots prepared from polyethylenimine for fluorometric determination of salivary uric acid.
Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 38 citations in OpenAlex.
- Purine Metabolism Dysfunctions: Experimental Methods of Detection and Diagnostic Potential.International journal of molecular sciences · 2023Review
- Article
- Novel LC-MS-TOF method to detect and quantify ascorbic and uric acid simultaneously in different biological matrices.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2021Article
- The analytical and biomedical applications of carbon dots and their future theranostic potential: A review.Journal of food and drug analysis · 2020Review
- Label-free detection of creatinine using nitrogen-passivated fluorescent carbon dots.RSC advances · 2020Article
- "Turn-on" fluorometric probe for α-glucosidase activity using red fluorescent carbon dots and 3,3',5,5'-tetramethylbenzidine.Mikrochimica acta · 2020Article
- A dual-signal colorimetric and ratiometric fluorescent nanoprobe for enzymatic determination of uric acid by using silicon nanoparticles.Mikrochimica acta · 2019Article
- The fluorescence mechanism of carbon dots, and methods for tuning their emission color: a review.Mikrochimica acta · 2019Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Stable and low-cost carbon dots (C-dots) were prepared from polyethylenimine (PEI) by a hydrothermal method. It is found that the fluorescence of the C-dots (best measured at excitation/emission wavelengths of 365/473 nm) is quenched by selective oxidation of surface PEI by periodate but recovers in the presence of uric acid (UA). It is assumed that this is due to the selective reduction of the nitrone groups to hydroxylamine groups by UA. The findings were used to design a fluorometric method for determination of UA that has a 2.3 nM detection limit. This is lower than that of reported fluorometric and enzymatic assays. The performance of the method has been validated by determination of UA in samples of human saliva. It is found that the results agree well with those obtained by a commercial UA assay. Graphical abstract Schematic presentation of the polyethylenimine (PEI) carbon nanodots (C-dots) as a fluorescent probe for uric acid. Their fluorescence is quenched by periodate (IO
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Registered trials
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