ArticleJournal of cancer research and clinical oncology2019
Cancer risk in stroke survivors followed for up to 10 years in general practices in Germany.
Article in Journal of cancer research and clinical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cancer risk subsequent to cardiovascular disease: a prospective population-based study and meta-analysis.BMC medicine · 2025Pooled it
- Ischemic Heart Disease, Hematological Malignancies, and Infectious Diseases as Risk Factors for Cervical Cancer: A Study Based on Korean National Health Insurance Data.Journal of clinical medicine · 2025Article
- A case of obstructive shock and transient ischemic attack from intracardiac metastasis of non-small cell lung cancer (NSCLC).Annals of medicine and surgery (2012) · 2025Article
- Epigenetic age and long-term cancer risk following a stroke.Genome medicine · 2024Article
- Personalised lung cancer risk stratification and lung cancer screening: do general practice electronic medical records have a role?British journal of cancer · 2023Article
- The crosstalk between Stroke and Cancer: Incidence of cancer after a first-ever cerebrovascular event in a population-based study.European stroke journal · 2023Article
- Association of Stroke at Young Age With New Cancer in the Years After Stroke Among Patients in the Netherlands.JAMA network open · 2023Article
- A risk model for prediction of diagnosis of cancer after ischemic stroke.Scientific reports · 2023Article
- Clinical practice: intravenous thrombolysis in a patient with active cancer who experienced wake-up stroke.The Journal of international medical research · 2021Article
- Fecal and urinary incontinence are major problems associated with rectal cancer.International journal of colorectal disease · 2020Article
- Increased risk for cancer after stroke at a young age: etiological relevance or incidental finding?Journal of cancer research and clinical oncology · 2019Article
- Cancer and Cerebrovascular Disease.Current neurology and neuroscience reports · 2019Review
- Clinical Characteristics and Risk Factors of Lung Cancer-Associated Acute Ischemic Stroke.BioMed research international · 2019Article
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Abstract
aimsThe goal of this study was to analyze cancer risk in stroke survivors followed for up to 10 years in general practices in Germany.
methodsThe current study sample included patients who received an initial stroke diagnosis in one of 1262 general practices in Germany between 2006 and 2015 (index date). Patients without stroke were matched (1:1) to patients with stroke by age, gender, index year, and 16 comorbidities diagnosed in the 12 months prior to the index date using a propensity score method. The main outcome of the study was the risk of cancer as a function of stroke within 10 years of the index date.
resultsThe stroke and non-stroke groups included 9579 men and 9089 women. After 10 years of follow-up, 29.3% of men with stroke and 23.8% of those without stroke developed any of the included types of cancer (log-rank p value < 0.001). During the same time, the prevalence of cancer was 25.0% in women with stroke and 20.5% in women without stroke (log-rank p value < 0.001). There was a positive association between stroke and any cancer in men (hazard ratio [HR] = 1.18, 95% confidence interval [CI] 1.09-1.28) and in women (HR = 1.22, 95% CI 1.12-1.34). This association was significant for cancers of respiratory and intrathoracic organs in men and women and for cancers of digestive organs in men.
conclusionsThis study, including more than 37,000 patients from Germany, found that stroke was associated with an increased cancer risk.
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