Evidence map›Paper›PMID 30738690›Full record

ArticleDiagnostic microbiology and infectious disease2019

Comparison of FTD® respiratory pathogens 33 and a singleplex CDC assay for the detection of respiratory viruses: A study from Cameroon.

Sebastien Kenmoe, Clarisse Tcharnenwa, Gwladys C Monamele, Cyprien Nde Kengne, Mohamadou Njankouo Ripa, Brett Whitaker, Karen A Alroy, S Arunmozhi Balajee, Richard Njouom

Open access · greenAbstract read
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  7. Diagnosing Tuberculosis: What Do New Technologies Allow Us to (Not) Do?Respiration; international review of thoracic diseases · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Sebastien KenmoeDepartment of Virology, Centre Pasteur of Cameroon, 451 Rue 2005, P.O. Box 1274, Yaoundé, Cameroon.
Clarisse TcharnenwaDepartment of Virology, Centre Pasteur of Cameroon, 451 Rue 2005, P.O. Box 1274, Yaoundé, Cameroon; Department of Microbiology, Faculty of Sciences, University of Yaoundé I, P.O. Box 337, Yaoundé, Cameroon.
Gwladys C MonameleDepartment of Virology, Centre Pasteur of Cameroon, 451 Rue 2005, P.O. Box 1274, Yaoundé, Cameroon; Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Cyprien Nde KengneNational AIDS Control Committee, Cameroon.
Mohamadou Njankouo RipaDepartment of Virology, Centre Pasteur of Cameroon, 451 Rue 2005, P.O. Box 1274, Yaoundé, Cameroon.
Brett WhitakerDivision of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Karen A AlroyDivision of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
S Arunmozhi BalajeeDivision of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Richard NjouomDepartment of Virology, Centre Pasteur of Cameroon, 451 Rue 2005, P.O. Box 1274, Yaoundé, Cameroon. Electronic address: njouom@pasteur-yaounde.org.
Centre Pasteur du Cameroun · CMCenters for Disease Control and Prevention · USNational Center for Immunization and Respiratory Diseases · USNational Radiation Protection Agency of Cameroon · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study compares the detection of 14 common respiratory viruses by two different real-time reverse transcription polymerase chain reaction (rRT-PCR) methods: in house singleplex tests developed by the Centers for Disease Control and Prevention and the commercially available Fast Track Diagnostic (FTD®) Respiratory Pathogens 33 multiplex test.

methodsA total of 217 nasopharyngeal swabs were analyzed using CDC singleplex rRT-PCR and FTD® Respiratory Pathogens 33 multiplex assays, for the detection of 14 respiratory viruses.

resultsThe results showed that 179/217 (82.5%) samples were positive with the singleplex method and 183/217 (84.3%) with the FTD® Respiratory Pathogens 33 multiplex test. Excellent or satisfactory agreement was obtained for all viruses (k > 0.6) except Parainfluenzavirus 4 (k = 0.24) and influenza B (k = 0.51).

conclusionAlthough the multiplex FTD kits were more expensive than the singleplex assay, the FTD kits yielded rapid results in a shorter timeframe, increasing efficiency of diagnosis.

Indexed as

AdolescentAdultAgedAged, 80 and overCameroonChildChild, PreschoolClinical Laboratory TechniquesDiagnostic Tests, RoutineFemaleHumansInfantInfant, NewbornMaleMiddle AgedMolecular Diagnostic TechniquesCameroonMolecular diagnosticRespiratory viruses

Identifiers

PMID30738690
PMCPMC7127211
OpenAlexW2910176109

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.