Evidence map›Paper›PMID 30737913›Full record

ArticleMicrobiology spectrum2019

Sortases, Surface Proteins, and Their Roles in

Olaf Schneewind, Dominique Missiakas

Open access · greenAbstract read
In one paragraph

Article in Microbiology spectrum, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 71 citations in OpenAlex.

  1. Review
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  13. Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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  20. The Transpeptidase Sortase A Binds Nucleic Acids and Mediates Mammalian Cell Labeling.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Olaf SchneewindDepartment of Microbiology, University of Chicago, Chicago, IL 60637.
Dominique MissiakasDepartment of Microbiology, University of Chicago, Chicago, IL 60637.
University of Chicago · US

Funding

Surface Proteins of Gram-Positive BacteriaR01AI038897 · NIAID · UNIVERSITY OF CHICAGO · PI MISSIAKAS, DOMINIQUE M. · 1996 to 2024
$8.9M
Vaccine Assembly from Surface Proteins of Staphylococcus AureusR01AI052474 · NIAID · UNIVERSITY OF CHICAGO · PI Dominique Missiakas · 2002 to 2026
$8.8M
Molecular basis and intervention of Staphylococcus aureus agglutinationR01AI110937 · NIAID · UNIVERSITY OF CHICAGO · PI MISSIAKAS, DOMINIQUE M. · 2015 to 2019
$1.8M
Molecular basis and intervention of Staphylococcus aureus agglutinationR56AI110937 · NIAID · UNIVERSITY OF CHICAGO · PI MISSIAKAS, DOMINIQUE M. · 2014 to 2014
$389k
NIAID NIH HHS R01 AI038897NIAID NIH HHS R01 AI052474NIAID NIH HHS R01 AI110937NIAID NIH HHS R56 AI110937
6 · The paper itself

Abstract

Sortases cleave short peptide motif sequences at the C-terminal end of secreted surface protein precursors and either attach these polypeptides to the peptidoglycan of Gram-positive bacteria or promote their assembly into pilus structures that are also attached to peptidoglycan. Sortase A, the enzyme first identified in the human pathogen

Indexed as

AminoacyltransferasesAntibodies, BacterialBacterial ProteinsCysteine EndopeptidasesHumansMembrane ProteinsPeptidoglycanStaphylococcal InfectionsStaphylococcal VaccinesStaphylococcus aureusAminoacyltransferasesAntibodies, BacterialBacterial ProteinsCysteine EndopeptidasesMembrane ProteinsPeptidoglycansortase AStaphylococcal Vaccines

Identifiers

PMID30737913
PMCPMC6386163
OpenAlexW2912002221

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.