Evidence map›Paper›PMID 30737889›Full record

Trial reportJournal of clinical hypertension (Greenwich, Conn.)2019

Acupuncture for patients with mild hypertension: A randomized controlled trial.

Hui Zheng, Juan Li, Ying Li, Ling Zhao, Xi Wu, Jie Chen, Xiang Li, Yin-Lan Huang, Xiao-Rong Chang, Mi Liu and 6 more

Abstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of clinical hypertension (Greenwich, Conn.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  8. Acupuncture for patients with mild hypertension: A randomized controlled trial.Journal of clinical hypertension (Greenwich, Conn.) · 2019
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  18. Acupuncture in Arterial Hypertension: Evaluation of its Efficacy with Both Office and Ambulatory Blood Pressure Measurements.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Hui ZhengAcupuncture and Tuina School/3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Juan LiCollege of Health Preservation and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Ying LiAcupuncture and Tuina School/3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Ling ZhaoAcupuncture and Tuina School/3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Xi WuAcupuncture and Tuina School/3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Jie ChenAcupuncture and Tuina School/3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Xiang LiAcupuncture and Tuina School/3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yin-Lan HuangTraditional Chinese Medicine Department, General Hospital of Ningxia Medicine University, Ningxia, China.
Xiao-Rong ChangAcupuncture and Tuina School, Hunan University of Traditional Chinese Medicine, Changsha, China.
Mi LiuAcupuncture and Tuina School, Hunan University of Traditional Chinese Medicine, Changsha, China.
Jin CuiAcupuncture and Tuina School, Guiyang University of Chinese Medicine, Guiyang, China.
Rui-Hui WangAcupuncture and Tuina School, Shaanxi University of Chinese Medicine, Xian, China.
Xu DuAcupuncture and Tuina School, Shaanxi University of Chinese Medicine, Xian, China.
Jing ShiAcupuncture and Tuina Department, Yunnan Provincial Hospital of Traditional Chinese Medicine, Kunming, China.
Tai-Pin GuoAcupuncture and Tuina School, Yunnan University of Traditional Chinese Medicine, Kunming, China.
Fan-Rong LiangAcupuncture and Tuina School/3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, China.ORCID 0000-0002-2705-4012

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acupuncture may be beneficial for patients with mild hypertension, but the evidence is not convincing. We aimed to examine the effect of acupuncture on blood pressure (BP) reduction in patients with mild hypertension. We conducted a multicenter, single-blind, sham-controlled, randomized trial in eleven hospitals in China. The trial included 428 patients with systolic blood pressure (SBP) from 140 to 159 mm Hg and/or with diastolic blood pressure (DBP) from 90 to 99 mm Hg. The patients were randomly assigned to receive 18 sessions of affected meridian acupuncture (n = 107) or non-affected meridian acupuncture (n = 107) or sham acupuncture (n = 107) during 6 weeks, or to stay in a waiting-list control (n = 107). All patients received 24-hour ambulatory blood pressure monitoring at weeks 6, 9, and 12. We included 415 participants in the intention-to-treat analysis. The two acupuncture groups were pooled in the analysis, since they had no difference in all outcomes. SBP decreased at week 6 in acupuncture group vs sham acupuncture vs waiting-list group (7.2 ± 11.0 mm Hg vs 4.1 ± 11.5 mm Hg vs 4.1 ± 13.2 mm Hg); acupuncture was not superior to sham acupuncture (mean difference 2.7 mm Hg, 95% CI 0.4 to 5.9, adjusted P = 0.103) or waiting-list control (2.9 mm Hg, 95% CI -0.2 to 6.0, adjusted P = 0.078). However, acupuncture was superior to sham acupuncture (3.3 mm Hg, 95% CI 0.2 to 6.3, adjusted P = 0.035) and waiting-list control (4.8 mm Hg, 95% CI 1.8 to 7.8, P < 0.001) at week 9. Acupuncture had a small effect size on the reduction of BP in patients with mild hypertension.

Indexed as

Acupuncture TherapyAgedBlood PressureBlood Pressure Monitoring, AmbulatoryCase-Control StudiesChinaFemaleHospitalsHumansHypertensionIntention to Treat AnalysisMaleMiddle AgedSingle-Blind Methodacupunctureblood pressure variabilitymild hypertensionrandomized controlled trial

Identifiers

PMID30737889
PMCPMC8030314

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.