Evidence map›Paper›PMID 30737882›Full record

ArticleJournal of biomedical materials research. Part A2019

Zinc-oxide nanoparticles act catalytically and synergistically with nitric oxide donors to enhance antimicrobial efficacy.

Priyadarshini Singha, Christina D Workman, Jitendra Pant, Sean P Hopkins, Hitesh Handa

Open access · greenAbstract read
In one paragraph

Article in Journal of biomedical materials research. Part A, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 38 citations in OpenAlex.

  1. Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Priyadarshini SinghaSchool of Chemical, Materials and Biomedical Engineering, College of Engineering, University of Georgia, Athens, Georgia.
Christina D WorkmanSchool of Chemical, Materials and Biomedical Engineering, College of Engineering, University of Georgia, Athens, Georgia.
Jitendra PantSchool of Chemical, Materials and Biomedical Engineering, College of Engineering, University of Georgia, Athens, Georgia.
Sean P HopkinsSchool of Chemical, Materials and Biomedical Engineering, College of Engineering, University of Georgia, Athens, Georgia.
Hitesh HandaSchool of Chemical, Materials and Biomedical Engineering, College of Engineering, University of Georgia, Athens, Georgia.
University of Georgia · US

Funding

Engineering nitric oxide releasing polymer with immobilized thrombin inhibitor for blood contacting applicationsR01HL134899 · NHLBI · UNIVERSITY OF GEORGIA · PI HANDA, HITESH · 2017 to 2025
$3.0M
Prevention of Thrombosis by NO Secreting PolymersK25HL111213 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HANDA, HITESH · 2012 to 2016
$739k
NHLBI NIH HHS K25 HL111213NHLBI NIH HHS K25HL111213NHLBI NIH HHS R01 HL134899NHLBI NIH HHS R01HL134899
6 · The paper itself

Abstract

The development of infection-resistant materials is of substantial importance as seen with an increase in antibiotic resistance. In this project, the nitric oxide (NO)-releasing polymer has an added topcoat of zinc oxide nanoparticle (ZnO-NP) to improve NO-release and match the endogenous NO flux (0.5-4 × 10

Indexed as

3T3 CellsAnimalsAnti-Bacterial AgentsBacterial AdhesionCatalysisCell SurvivalKineticsMiceMicrobial Sensitivity TestsMicrobial ViabilityNanoparticlesNitric OxideNitric Oxide DonorsS-Nitroso-N-AcetylpenicillamineSpectrometry, X-Ray EmissionZinc OxideAnti-Bacterial AgentsNitric OxideNitric Oxide DonorsS-Nitroso-N-AcetylpenicillamineZinc Oxideantimicrobialcatalysismedical device coatingnitric oxidezinc oxide nanoparticle

Identifiers

PMID30737882
PMCPMC6527449
OpenAlexW2914586722

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.