Evidence map›Paper›PMID 30737845›Full record

ArticleJournal of clinical laboratory analysis2019

Neutrophil-to-lymphocyte ratio can specifically predict the severity of hypertriglyceridemia-induced acute pancreatitis compared with white blood cell.

Li Huang, Congying Chen, Lijuan Yang, Rong Wan, Guoyong Hu

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Li HuangDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0001-8448-3481
Congying ChenDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lijuan YangDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Rong WanDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Guoyong HuDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shanghai Jiao Tong University · CN

Funding

Natural Science Foundation of China 81800566Shanghai Committee of Science and Technology, Shanghai Natural Science Foundation 17ZR1422700
6 · The paper itself

Abstract

objectivesWe aimed to evaluate the values of neutrophil-to-lymphocyte ratio (NLR) and white blood cell (WBC) in predicting severity of acute pancreatitis (AP) with different etiologies.

methodsWe compared NLR and WBC levels in patients with different etiologies and AP severity. The optimal cutoff value for them to predict severe acute pancreatitis (SAP) was determined by receiver operating characteristic (ROC) curve analysis.

resultsBoth NLR and WBC were elevated in patients with SAP. After subgrouping AP by etiology, NLR was predictive of SAP only in hypertriglyceridemia-induced AP (HTG-AP), while WBC could effectively predict severity in both gallstone and HTG-AP. The best cutoff value of WBC for predicting SAP in gallstone AP patients was 12.81 × 10

conclusionsOur study firstly demonstrated that NLR selectively played a role in HTG-AP, while WBC could predict the severity of both gallstone and HTG-AP. Furthermore, we firstly elucidated that NLR was more sensitive and accurate in judging the severity of HTG-AP compared with WBC.

Indexed as

Lymphocyte CountNeutrophilsAcute DiseaseAdultAgedFemaleHumansHypertriglyceridemiaLeukocyte CountMaleMiddle AgedPancreatitisROC CurveSensitivity and Specificityacute pancreatitisalcoholicgallstoneshypertriglyceridemianeutrophil-to-lymphocyte ratio

Identifiers

PMID30737845
PMCPMC6528595
OpenAlexW2912149851

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.