Evidence map›Paper›PMID 30737724›Full record

ArticleJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology2019

Editor's Commentary for Special Issue: "The Role of Macrophages in HIV Persistence".

Tricia H Burdo

Abstract read
In one paragraph

Article in Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The reservoir of latent HIV.Frontiers in cellular and infection microbiology · 2022
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Tricia H BurdoDepartment of Neuroscience, Temple University School of Medicine, 3500 North Broad Street, MERB 755, Philadelphia, PA, 19140, USA. burdot@temple.edu.
Temple University · US

Funding

REPRIEVE COVID-19 Administrative SupplementU01HL123336 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI DOUGLAS, PAMELA SUSAN, GRINSPOON, STEVEN K. · 2014 to 2021
$52.4M
Viral Gene Editing and Bioinformatics Core for Institution # 269291P30MH092177 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI SHOHREH AMINI · 2011 to 2026
$24.9M
Functional Imaging Reserve in NeuroHIV (FIRN)R01MH118031 · NIMH · WASHINGTON UNIVERSITY · PI ANCES, BEAU M · 2018 to 2023
$3.7M
Cardiovascular Disease Risk in HIV-infected Women: Sex-Specific Mechanisms of Risk and Risk Reduction among REPRIEVE Trial ParticipantsR01AI123001 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI LOOBY, SARA ELIZABETH DOLAN, ZANNI, MARKELLA V. · 2015 to 2019
$3.4M
Exercise Training to Improve Brain Health in Older HIV+ IndividualsR01NR015738 · NINR · WASHINGTON UNIVERSITY · PI ANCES, BEAU M · 2015 to 2019
$3.0M
Role of caspase-1 activation in HIV-1 associated atherogenesisR01HL141132 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI BURDO, TRICIA HELEN, QIN, XUEBIN · 2018 to 2021
$2.5M
Atherogenic roles of complement systemR01HL130233 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI QIN, XUEBIN, WANG, HONG · 2016 to 2019
$2.5M
Impact of HIV Infection on Myocardial Cell HomeostasisR01HL141045 · NHLBI · UNIVERSITY OF CENTRAL FLORIDA · PI GUPTA, MANISH KUMAR · 2018 to 2021
$2.1M
NHLBI NIH HHS R01 HL130233NHLBI NIH HHS R01 HL141045NHLBI NIH HHS R01 HL141132NHLBI NIH HHS U01 HL123336NIAID NIH HHS R01 AI123001NIH HHS R01 AI123001NIH HHS R01 HL141045NIH HHS R01 MH118031NIH HHS R01 NR015738NIMH NIH HHS P30 MH092177NIMH NIH HHS R01 MH118031NINR NIH HHS R01 NR015738
6 · The paper itself

Abstract

Macrophages as reservoirs for persistent HIV infection has gained renewed importance, with an intense research focus dedicated to eradication strategies. Clearance of both latent and productive HIV from these important reservoirs is essential for successful eradication. This spe cial theme issue contains 11 papers, including 6 Invited Reviews, 1 Brief Report and 4 Original Articles, that focus on the various aspects of the macrophage as pertains to HIV persistence, latency and cure. These topics include: functional latency of macrophages and microglia, the link between peripheral monocytes and pathogenesis, macrophages as sources of HIV RNA and DNA in virally suppressed patients, brain imaging of neuroinflammation, macrophages as drug delivery vehicles, therapeutic strategies of infected macrophages for cure, and the role of drugs of abuse in enhancing macrophage viral persistence.

Indexed as

AnimalsHIVHIV InfectionsHumansMacrophagesVirus LatencyHIVLatencyMacrophageReservoir

Identifiers

PMID30737724
PMCPMC6424350
OpenAlexW2912743143

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.