Evidence map›Paper›PMID 30737607›Full record

ReviewInflammopharmacology2019

Prevalence and current therapy in chronic liver disorders.

Muhammad Daniyal, Muhammad Akram, Rida Zainab, Naveed Munir, Aamir Sharif, Syed Muhammad Ali Shah, Bin Liu, Wei Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Inflammopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. A comprehensive review ofFrontiers in pharmacology · 2022
    Review
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Muhammad DaniyalTCM and Ethnomedicine Innovation and Development International Laboratory, School of Pharmacy, Innovative Materia Medica Research Institute, Hunan University of Chinese Medicine, Changsha, 410208, People's Republic of China.
Muhammad AkramDepartment of Eastern Medicine, Directorate of Medical Sciences, Government College University, Faisalabad, Pakistan.
Rida ZainabDepartment of Eastern Medicine, Directorate of Medical Sciences, Government College University, Faisalabad, Pakistan. ridazainab357@gmail.com.
Naveed MunirDepartment of Biochemistry and College of Allied health professionals, Directorate of Medical sciences, Government College University, Faisalabad, Pakistan.
Aamir SharifDepartment of Pathology, Faculty of Medical and Health Sciences, University of Sargodha, Sargodha, Pakistan.
Syed Muhammad Ali ShahDepartment of Eastern Medicine, Directorate of Medical Sciences, Government College University, Faisalabad, Pakistan.
Bin LiuHunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, College of Biology, Hunan University, Changsha, 410082, China.
Wei WangTCM and Ethnomedicine Innovation and Development International Laboratory, School of Pharmacy, Innovative Materia Medica Research Institute, Hunan University of Chinese Medicine, Changsha, 410208, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHerbal medicine plays an important role in health, particularly in remote parts of developing areas with few health facilities. According to WHO estimates, about three-quarters of the world's population currently use herbs or traditional medicines to treat various ailments, including liver diseases. Several studies have found that the use of medicinal plants was effective in the treatment of infectious and non-infectious diseases. Hepatitis and liver cirrhosis associated with many clinical manifestations can be treated with allopathic medicines, but reports of a number of side effects including immunosuppression, bone marrow suppression, and renal complications have motivated researchers to explore more natural herbal medicines with low or no side effects and with high efficacy in treating hepatic diseases.

methodsDatabases including PubMed, Medline, and Google Scholar were searched for findings on the hepatoprotective effects of plants.

resultsVarious medicinal plants are used for the treatment of liver disorders. The range of alternative therapies is huge, and they are used worldwide, either as part of primary health care or in combination with conventional medicine. Hepatoprotective plants contain a variety of chemical constituents including flavonoids, alkaloids, glycosides, carotenoids, coumarins, phenols, essential oil, organic acids, monoterpenes, xanthenes, lignans, and lipids.

conclusionThis review shows that numerous plants are found to contain hepatoprotective compounds. However, further studies are needed to determine their association with existing regimes of antiviral medicines and to develop evidence-based alternative medicine to cure different kinds of liver disease in humans.

Indexed as

AnimalsChronic DiseaseHerbal MedicineHumansLiver DiseasesPlant PreparationsPrevalencePlant PreparationsAllopathic medicineEfficacyHepatoprotective activityLiterature reviewLiver disordersMedicinal plantsSide effects

Identifiers

PMID30737607

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.