ArticleEuropean radiology2019
Feasibility of low-dose CT with spectral shaping and third-generation iterative reconstruction in evaluating interstitial lung diseases associated with connective tissue disease: an intra-individual comparison study.
Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 18 citations in OpenAlex.
- Low-dose vs standard-dose photon-counting CT for myopathy-associated interstitial lung disease: a prospective feasibility study.European radiology · 2026Article
- Application of deep learning reconstruction at prone position chest scanning of early interstitial lung disease.BMC medical imaging · 2025Article
- Evaluation of a content-based image retrieval system for radiologists in high-resolution CT of interstitial lung diseases.European radiology experimental · 2025Article
- Impact of the ADMIRE reconstruction algorithm combined with the Sa36 kernel on quantitative measurement of coronary artery calcification in AI: a single-arm prospective study.Polish journal of radiology · 2025Article
- Different clinicopathological features between young and older patients with pulmonary adenocarcinoma and ground-glass opacity.Scientific reports · 2024Article
- Value of deep learning reconstruction of chest low-dose CT for image quality improvement and lung parenchyma assessment on lung window.European radiology · 2024Article
- Can deep learning improve image quality of low-dose CT: a prospective study in interstitial lung disease.European radiology · 2022Article
- Management of Connective Tissue Disease-related Interstitial Lung Disease.Current pulmonology reports · 2022Review
- Quantification of pulmonary vessel volumes on low-dose computed tomography in a healthy male Chinese population: the effects of aging and smoking.Quantitative imaging in medicine and surgery · 2022Article
- Third-generation iterative reconstruction on a dual-source, high-pitch, low-dose chest CT protocol with tin filter for spectral shaping at 100 kV: a study on a small series of COVID-19 patients.La Radiologia medica · 2021Article
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7 authors at 3 institutions in 1 country.
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Abstract
objectivesTo investigate the feasibility of low-dose CT (LDCT) with tin filtration and third-generation iterative reconstruction (IR) in evaluating interstitial lung diseases associated with connective tissue disease (CTD-ILD).
methodsFifty-three consecutive adult patients with CTD-ILD underwent regular-dose chest CT (RDCT) at 110 kVp followed by LDCT with tin-filtered 100 kVp. RDCT was reconstructed with filtered back projection (FBP) and advanced modeled iterative reconstruction (ADMIRE); LDCT was reconstructed with ADMIRE. Image noise, streak artifact, image quality, and visualization of normal and abnormal CT features were evaluated and compared among RDCT-ADMIRE, RDCT-FBP, and LDCT-ADMIRE groups.
resultsThe mean radiation dose of LDCT was reduced to 20% of RDCT. Objective image noise of RDCT-ADMIRE (38.08 ± 6.37 HU), LDCT-ADMIRE (51.68 ± 9.06 HU), and RDCT-FBP (62.09 ± 10.95 HU) increased progressively (p < 0.001 in any two pairs). RDCT-ADMIRE significantly improved subjective image noise, streak artifact, and overall image quality compared with RDCT-FBP and LDCT-ADMIRE (all p < 0.001), while no significant difference was noted between the latter two groups. All abnormal lung structures were better scored in RDCT-ADMIRE compared with those in RDCT-FBP (all p < 0.001). LDCT-ADMIRE was inferior to RDCT-FBP in visualizing peripheral bronchi and vessels as well as reticulation (all p < 0.001); other normal and abnormal structures were similar between the two groups.
conclusionLDCT with tin filtration and third-generation IR was applicable in evaluating ILD lesions of CTD. Image quality was significantly improved after applying ADMIRE algorithm to CT protocols. KEY POINTS: • Optimization of CT radiation dose is a clinical concern in patients with connective tissue disease. • Spectral shaping and third-generation iterative reconstruction emerge as promising techniques in reducing radiation dose and acquiring desired image quality of CTD-ILD patients. • The third-generation iterative reconstruction algorithm can optimize visualization of ILD patterns in low-dose CT.
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