ArticleEuropean journal of applied physiology2019
Capsaicin supplementation increases time to exhaustion in high-intensity intermittent exercise without modifying metabolic responses in physically active men.
Article in European journal of applied physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Effects of acute Capsaicin analogue intake on athletic performance: a three-level meta-analysis.Journal of the International Society of Sports Nutrition · 2026Pooled it
- Pooled it
- Acute phenylcapsaicin supplementation improves CrossFit® performance: a randomized, triple-blind, placebo-controlled crossover trial.Journal of the International Society of Sports Nutrition · 2026Trial
- Capsaicin and Its Effect on Exercise Performance, Fatigue and Inflammation after Exercise.Nutrients · 2022Trial
- Dihydrocapsiate does not increase energy expenditure nor fat oxidation during aerobic exercise in men with overweight/obesity: a randomized, triple-blinded, placebo-controlled, crossover trial.Journal of the International Society of Sports Nutrition · 2022Trial
- Trial
- Multi-ingredient pre-workout supplementation changes energy system contribution and improves performance during high-intensity intermittent exercise in physically active individuals: a double-blind and placebo controlled study.Journal of the International Society of Sports Nutrition · 2020Trial
- The Effects of Post-Activation Performance Enhancement on High Intensity Interval Training: A Comparison of Traditional and Cluster Set Protocols.European journal of sport science · 2026Article
- Exploring Cyclodextrin Complexes of Lipophilic Antioxidants: Benefits and Challenges in Nutraceutical Development.International journal of molecular sciences · 2025Review
- Acute effects of multi-ingredient pre-workout dietary supplement on anaerobic performance in untrained men: a randomized, crossover, single blind study.BMC sports science, medicine & rehabilitation · 2024Article
- A natural sustained-intestinal release formulation of red chili pepper extracted capsaicinoids (Capsifen®) safely modulates energy balance and endurance performance: a randomized, double-blind, placebo-controlled study.Frontiers in nutrition · 2024Article
- Effects of phenylcapsaicin on aerobic capacity and physiological parameters in active young males: a randomized, triple-blinded, placebo-controlled, crossover trial.Frontiers in physiology · 2023Article
- Acute Supplementation with Capsaicin Enhances Upper-Limb Performance in Male Jiu-Jitsu Athletes.Sports (Basel, Switzerland) · 2022Article
- Can taste be ergogenic?European journal of nutrition · 2021Review
- Effect of a Commercially Available Low-Dose Capsaicin Supplement on Knee Extensor Contractile Function.International journal of exercise science · 2020Article
- Commercially Available Capsaicin Supplement Fails to Enhance Time-to-Exhaustion During Cycling.International journal of exercise science · 2020Article
Corrections and comments
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Authors and funding
7 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to investigate the acute effect of capsaicin supplementation on performance and physiological responses during high-intensity intermittent exercise (HIIE).
methodThirteen physically active men (age = 24.4 ± 4.0 years; height = 176.4 ± 6.9 cm; body mass = 78.7 ± 13.8 kg; running training per week = 3.9 ± 0.9 h) performed an incremental running test to determine peak oxygen uptake ([Formula: see text]) and the speed associated with [Formula: see text] (s[Formula: see text]). Thereafter, subjects completed two randomized, double-blind HIIE (15s:15 s at 120% s[Formula: see text]) trials 45-min after consuming capsaicin (12 mg) or an isocaloric placebo. Time to exhaustion, blood lactate concentration, oxygen consumption during and 20 min post-exercise, energy expenditure, time spent above 90% of [Formula: see text], and the rate of perceived exertion were evaluated.
resultsThere was no difference between capsaicin and placebo for any variable except time to exhaustion [capsaicin: 1530 ± 515 s (102 efforts) vs placebo: 1342 ± 446 s (89 efforts); p < 0.001].
conclusionIn conclusion, capsaicin supplementation increased time to exhaustion in high-intensity intermittent exercise without modifying the metabolic response of exercise or the rate of perceived exertion in physically active men. Capsaicin could be used to increase the training load during specific exercise training sessions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.