Evidence map›Paper›PMID 30737439›Full record

ArticleScientific reports2019

A Novel Ruthenium-based Molecular Sensor to Detect Endothelial Nitric Oxide.

Achini K Vidanapathirana, Benjamin J Pullen, Run Zhang, MyNgan Duong, Jarrad M Goyne, Xiaozhou Zhang, Claudine S Bonder, Andrew D Abell, Christina A Bursill, Stephen J Nicholls and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Achini K VidanapathiranaVascular Research Centre, Heart Health Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, 5000, Australia.ORCID 0000-0003-0126-799X
Benjamin J PullenVascular Research Centre, Heart Health Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, 5000, Australia.
Run ZhangAustralian Research Council (ARC) Centre of Excellence for Nanoscale BioPhotonics (CNBP), Adelaide, Australia.ORCID 0000-0002-0943-824X
MyNgan DuongVascular Research Centre, Heart Health Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, 5000, Australia.
Jarrad M GoyneVascular Research Centre, Heart Health Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, 5000, Australia.
Xiaozhou ZhangAustralian Research Council (ARC) Centre of Excellence for Nanoscale BioPhotonics (CNBP), Adelaide, Australia.
Claudine S BonderAdelaide Medical School, University of Adelaide, Adelaide, South Australia, 5000, Australia.ORCID 0000-0001-9875-967X
Andrew D AbellAustralian Research Council (ARC) Centre of Excellence for Nanoscale BioPhotonics (CNBP), Adelaide, Australia.
Christina A BursillVascular Research Centre, Heart Health Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, 5000, Australia.
Stephen J NichollsVascular Research Centre, Heart Health Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, 5000, Australia.
Peter J PsaltisVascular Research Centre, Heart Health Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, 5000, Australia. peter.psaltis@sahmri.com.
Australian Research Council · AUCentre for Cancer Biology · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nitric oxide (NO) is a key regulator of endothelial cell and vascular function. The direct measurement of NO is challenging due to its short half-life, and as such surrogate measurements are typically used to approximate its relative concentrations. Here we demonstrate that ruthenium-based [Ru(bpy)

Indexed as

Biosensing TechniquesCell ProliferationCell SurvivalEndothelial CellsHumansHuman Umbilical Vein Endothelial CellsNitric OxideOrganometallic CompoundsPlasmaRutheniumNitric OxideOrganometallic CompoundsRuthenium

Identifiers

PMID30737439
PMCPMC6368587
OpenAlexW2913183073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.