ArticleNature communications2019
Population-wide analysis of differences in disease progression patterns in men and women.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
122 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Gender-Sensitive Nursing: An Operationalizing Concept Analysis.Journal of clinical nursing · 2026Pooled it
- Sex-stratified genome-wide meta-analysis identifies novel loci for cognitive decline in older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Pooled it
- Analysis of gender perspective in the use of NANDA-I nursing diagnoses: A systematic review.Nursing open · 2023Pooled it
- Sex-dependent associations of low birth weight and suicidal ideation in adulthood: a community-based cohort study.Scientific reports · 2020Trial
- LPS stimulation reveals male and female dimorphism in human iPSC-derived macrophages.iScience · 2026Article
- Article
- Unsupervised characterization of 100,272 EHR patients identifies high-risk groups and comorbidities linked to premature aging.NPJ digital medicine · 2026Article
- Gender differences in Myasthenia Gravis in a neuromuscular reference center in Belgium.Acta neurologica Belgica · 2026Article
- Multimorbidity trajectories and their sex-specific impacts on risk of mortality and re-hospitalisation.Scientific reports · 2026Article
- SASdb: a comprehensive database for sex-biased alternative splicing profiles in human tissues.Biology of sex differences · 2026Article
- Global burden of thyroid cancer in males: a comprehensive analysis of incidence, mortality, and risk factors from 1990 to 2040.Frontiers in oncology · 2026Article
- Meta-analysis of the association between marital status and hypertension: evaluating the impact of age and gender.American journal of cardiovascular disease · 2026Review
- Advancing women's health through equity in quantitative sciences: promoting sex- and gender-based modeling in clinical trials and real-world studies.Frontiers in digital health · 2026Article
- Sex-specific transcriptome similarity networks elucidate comorbidity relationships.Communications medicine · 2025Article
- Intersectoral action to transform health equity for women and girls globally.Communications medicine · 2025Review
- Contribution of Sex-Biased Expressed Genes in Osteoarthritis.Smart medicine · 2025Article
- Beyond Binary Policy: Precision Medicine Requires Sex-Inclusive Research.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- The impact of fear of cancer recurrence on anxiety and depression in women with cancer: The chain mediating roles of financial toxicity and psychological distress - A multicenter investigative study.Asia-Pacific journal of oncology nursing · 2025Article
- Postfeminist Healthism: Understanding the Gendering of Healthism Using Menstrual Tracking Apps as an Example.Sociology of health & illness · 2025Article
- Women's health research funding in Canada across 15 years suggests low funding levels with a narrow focus.Biology of sex differences · 2025Article
62 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sex-stratified medicine is a fundamentally important, yet understudied, facet of modern medical care. A data-driven model for how to systematically analyze population-wide, longitudinal differences in hospital admissions between men and women is needed. Here, we demonstrate a systematic analysis of all diseases and disease co-occurrences in the complete Danish population using the ICD-10 and Global Burden of Disease terminologies. Incidence rates of single diagnoses are different for men and women in most cases. The age at first diagnosis is typically lower for men, compared to women. Men and women share many disease co-occurrences. However, many sex-associated incongruities not linked directly to anatomical or genomic differences are also found. Analysis of multi-step trajectories uncover differences in longitudinal patterns, for example concerning injuries and substance abuse, cancer, and osteoporosis. The results point towards the need for an increased focus on sex-stratified medicine to elucidate the origins of the socio-economic and ethological differences.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.