Evidence map›Paper›PMID 30737287›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids.

Oliver W Bayfield, Evgeny Klimuk, Dennis C Winkler, Emma L Hesketh, Maria Chechik, Naiqian Cheng, Eric C Dykeman, Leonid Minakhin, Neil A Ranson, Konstantin Severinov and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. The Expanding Diversity of Viruses from Extreme Environments.International journal of molecular sciences · 2024
    Review
  8. Review
  9. Review
  10. Viral Genomic DNA Packaging Machinery.Sub-cellular biochemistry · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. A Capsid Structure ofViruses · 2022
    Article
  16. Terminase Subunits from the Pseudomonas-Phage E217.Journal of molecular biology · 2022
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Oliver W BayfieldYork Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom.ORCID 0000-0003-1421-7780
Evgeny KlimukCenter for Life Sciences, Skolkovo Institute of Science and Technology, 143025 Skolkovo, Russia.ORCID 0000-0001-5314-038X
Dennis C WinklerLaboratory of Structural Biology Research, National Institute of Arthritis Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0003-1445-6554
Emma L HeskethAstbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom.ORCID 0000-0002-4522-0061
Maria ChechikYork Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom.ORCID 0000-0001-8413-4230
Naiqian ChengLaboratory of Structural Biology Research, National Institute of Arthritis Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892.
Eric C DykemanDepartment of Mathematics, University of York, York YO10 5DD, United Kingdom.
Leonid MinakhinWaksman Institute for Microbiology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854.ORCID 0000-0003-0301-7054
Neil A RansonAstbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom.ORCID 0000-0002-3640-5275
Konstantin SeverinovCenter for Life Sciences, Skolkovo Institute of Science and Technology, 143025 Skolkovo, Russia.ORCID 0000-0001-9706-450X
Alasdair C StevenLaboratory of Structural Biology Research, National Institute of Arthritis Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0003-4104-6497
Alfred A AntsonYork Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom; fred.antson@york.ac.uk.ORCID 0000-0002-4533-3816
National Institutes of Health · USUniversity of York · GBRutgers, The State University of New Jersey · USUniversity of Leeds · GBSkolkovo Institute of Science and Technology · RU

Funding

The Function of Small RNA-Based viral Defense System in E. coli - Renewal 1R01GM104071 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI SEMENOVA, EKATERINA · 2013 to 2024
$3.9M
NIGMS NIH HHS R01 GM104071Wellcome Trust 108466Wellcome Trust 206377Wellcome Trust 206377/Z/17/Z
6 · The paper itself

Abstract

Double-stranded DNA viruses, including bacteriophages and herpesviruses, package their genomes into preformed capsids, using ATP-driven motors. Seeking to advance structural and mechanistic understanding, we established in vitro packaging for a thermostable bacteriophage, P23-45 of

Indexed as

BacteriophagesCapsidCryoelectron MicroscopyDNA PackagingDNA, ViralDNA VirusesVirionVirus AssemblyDNA, Viralcapsidcryo-EMDNA packagingportal proteinvirus assembly

Identifiers

PMID30737287
PMCPMC6397560
OpenAlexW2913226953

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.