Evidence map›Paper›PMID 30737135›Full record

ArticleBioorganic & medicinal chemistry2019

SYA 013 analogs as moderately selective sigma-2 (σ

Lamya Al-Ghanim, Xue Y Zhu, Gladys Asong, Seth Y Ablordeppey

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioorganic & medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lamya Al-GhanimDivision of Basic Pharmaceutical Sciences, Florida A&M University, College of Pharmacy and Pharmaceutical Sciences, Tallahassee, FL 32307, USA.
Xue Y ZhuDivision of Basic Pharmaceutical Sciences, Florida A&M University, College of Pharmacy and Pharmaceutical Sciences, Tallahassee, FL 32307, USA.
Gladys AsongDivision of Basic Pharmaceutical Sciences, Florida A&M University, College of Pharmacy and Pharmaceutical Sciences, Tallahassee, FL 32307, USA.
Seth Y AblordeppeyDivision of Basic Pharmaceutical Sciences, Florida A&M University, College of Pharmacy and Pharmaceutical Sciences, Tallahassee, FL 32307, USA. Electronic address: seth.ablordeppey@famu.edu.

Funding

THE PREVENTION OF B(A)P INDUCED CELL TRANSFORMATION BY ORGANOSULFUR COMPOUNDSG12RR003020 · NCRR · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · PI SOLIMAN, KARAM F.A. · 1985 to 2011
$29.7M
Recruitment and HiringG12MD007582 · NIMHD · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · PI SOLIMAN, KARAM F.A. · 2012 to 2017
$16.0M
A New Approach for the Development of Novel Antipsychotic DrugsSC1GM116724 · NIGMS · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · PI ABLORDEPPEY, SETH Y · 2016 to 2019
$1.4M
PHARMACEUTICAL RESEARCH CENTERC06RR012512 · NCRR · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · PI LEWIS, HENRY · 1997 to 1997
–
NCRR NIH HHS C06 RR012512NCRR NIH HHS G12 RR003020NIGMS NIH HHS SC1 GM116724NIMHD NIH HHS G12 MD007582NIMH NIH HHS HHSN271201300017C
6 · The paper itself

Abstract

Several lines of evidence suggest that selective sigma-2 (σ

Indexed as

AnimalsAzepinesHaloperidolHumansLigandsPiperazineProtein BindingReceptors, sigmaStructure-Activity Relationship4-(4-(4-chlorophenyl)-1,4-diazepan-1-yl)-1-(4-fluorophenyl)butan-1-oneAzepinesHaloperidolLigandsPiperazineReceptors, sigmasigma-2 receptor

Identifiers

PMID30737135
PMCPMC6536313

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.