ArticleOrphanet journal of rare diseases2019
Primary pulmonary lymphoma in children.
Article in Orphanet journal of rare diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 17 citations in OpenAlex.
- Persistent cough with unexplained endobronchial mass.World journal of pediatrics : WJP · 2025Article
- Primary pulmonary lymphoma in Peru.Ecancermedicalscience · 2023Article
- Role of 18F-FDG PET/CT in patients affected by pulmonary primary lymphoma.Frontiers in oncology · 2022Article
- Clinicopathological characteristics and prognostic factors of primary pulmonary lymphoma.Journal of thoracic disease · 2021Article
- Primary Pulmonary B-Cell Lymphoma: A Review and Update.Cancers · 2021Review
- Primary pulmonary diffuse large B-cell lymphoma with multiple ground-glass nodules as the primary manifestation: A case report.Medicine · 2020Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary pulmonary lymphoma (PPL) is a rare disease, especially in children. We analyse the clinical features of PPL in 4 children to strengthen a understanding of it.
resultsWe reported a case series of 4 pediatric patients with PPLs including three diffuse large B-cell lymphomas and one natural killer-T cell lymphoma. All patients presented with unknown fever and cough as well as weight loss and fatigue. The white blood cell count was reduced in three patients and increased in the other one. The level of C-reactive protein was increased in all patients. The procalcitonin concentrations and bone marrow specimens were normal. Multiple or single pulmonary nodules with halo signs were found in all patients and air bronchograms found in 3 of them on chest computed tomography scan. Primary immunodeficiency was diagnosed in two patients who was performed genetic analysis.
conclusionsWhen a patient presents with long-term fever, high C-reactive protein level, leukopenia/leukocytosis, and multiple or single pulmonary nodules with a "halo sign" and air bronchogram on computed tomography, a possibility of PPL should be considered. A co-existance of immunodeficiency needs to be further investigated in patients with PPL.
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