Evidence map›Paper›PMID 30736737›Full record

ArticleBMC geriatrics2019

Constipation and laxative use among people living in nursing homes in 2007 and 2013.

Maria Gustafsson, Kristina Lämås, Ulf Isaksson, Per-Olof Sandman, Hugo Lövheim

Open access · goldAbstract read
In one paragraph

Article in BMC geriatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Prevalence of Opioid Use in Nursing Homes Over the Last Decade: A Systematic Literature Review.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2024
    Article
  5. Observational
  6. Review
  7. The Burden and Treatment of Chronic Constipation Among US Nursing Home Residents.Journal of the American Medical Directors Association · 2023
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Laxative use in patients with advanced chronic kidney disease transitioning to dialysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Maria GustafssonDepartment of Pharmacology and Clinical Neuroscience, Umeå University, SE-901 87, Umeå, Sweden. maria.gustafsson@umu.se.ORCID 0000-0003-3615-4880
Kristina LämåsDepartment of Nursing, Umeå University, 901 87, Umeå, Sweden.
Ulf IsakssonDepartment of Nursing, Umeå University, 901 87, Umeå, Sweden.
Per-Olof SandmanDepartment of Nursing, Umeå University, 901 87, Umeå, Sweden.
Hugo LövheimDepartment of Community Medicine and Rehabilitation, Geriatric Medicine, Umeå University, 901 87, Umeå, Sweden.
Umeå University · SEArctic Research Centre · SEKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConstipation is a common condition among older people, particularly among people living in nursing homes, and the use of drugs such as opioids is one of many factors that contribute to its high prevalence. The aim of this study was to compare the prevalence of constipation and the use of laxatives between 2007 and 2013, to analyze constipation and laxative use among people who are prescribed opioids, and to identify factors associated with constipation.

methodsIn 2007 and 2013, two surveys were performed in the county of Västerbotten in Northern Sweden, comprising all those living in nursing homes. The Multi-Dimensional Dementia Assessment Scale was used to collect data regarding laxative, opioid and anticholinergic drug use, functioning in activities of daily living (ADL), cognition and symptoms of constipation. A comparison was made between 2820 people from 2007 and 1902 people from 2013.

resultsThe prevalence of symptoms of constipation among people living in nursing homes increased from 36% in 2007 to 40% in 2013. After controlling for age, sex, ADL, cognitive impairment and use of opioid and anticholinergic drugs, this difference was found to be statistically significant. When controlled for demographic changes, there was a statistically significant difference in the regular use of laxatives between the respective years, from 46% in 2007 to 59% in 2013. People prescribed opioids and anticholinergic drugs were at increased risk of constipation, while people with a higher ADL score were at decreased risk. Further, among people prescribed opioids and rated as constipated, 35% in 2007 and 20% in 2013 were not prescribed laxatives for regular use, a difference that was found to be statistically significant.

conclusionsThe prevalence of symptoms of constipation increased between 2007 and 2013. Although there was a decrease between the years, there were still a number of people being prescribed with opioids and rated as constipated who were not treated with laxatives. This study therefore indicates that constipation remains a significant problem among people in nursing homes and also indicates that those prescribed opioids could benefit from an increased awareness of the risk of constipation and treatment, if required.

Indexed as

Activities of Daily LivingAgedAged, 80 and overAnalgesics, OpioidCognitive DysfunctionConstipationFemaleHumansLaxativesMaleNursing HomesSurveys and QuestionnairesSwedenAnalgesics, OpioidLaxativesConstipationDementiaLaxativesNursing homes

Identifiers

PMID30736737
PMCPMC6368797
OpenAlexW2916970107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.