Evidence map›Paper›PMID 30736479›Full record

ArticleNutrients2019

The Beneficial Effects of Lactobacillus plantarum PS128 on High-Intensity, Exercise-Induced Oxidative Stress, Inflammation, and Performance in Triathletes.

Wen-Ching Huang, Chen-Chan Wei, Chi-Chang Huang, Wen-Lin Chen, Hui-Yu Huang

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04530929 (Analysis of the Impact of Used Probiotic Strains and Diet on Body Composition, Cardiopulmonary Efficiency and the Incidence of Gastrointestinal Disorders in Runners), which is not on this map. Cited by 89 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed, 15 pooled it
12.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04530929 nacompletednot on this map

Analysis of the Impact of Used Probiotic Strains and Diet on Body Composition, Cardiopulmonary Efficiency and the Incidence of Gastrointestinal Disorders in Runners

TypeinterventionalSponsorMedical University of BialystokRan2018 to 2018Enrolled66ConditionsGastrointestinal Disorder, FunctionalArmsSANPROBI BARRIER, PLACEBO
3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 15 syntheses or guidelines pooled it, 152 citations in OpenAlex.

  1. Effects ofFrontiers in nutrition · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Pooled it
  14. Impact of Probiotics on the Performance of Endurance Athletes: A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
  15. Meta-Analysis: Randomized Trials ofFrontiers in immunology · 2021
    Pooled it
  16. Trial
  17. Trial
  18. Trial
  19. Efficacy ofNutrients · 2024
    Trial
  20. Trial

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Wen-Ching HuangDepartment of Exercise and Health Science, National Taipei University of Nursing and Health Sciences, Taipei 11219, Taiwan. wenching@ntunhs.edu.tw.
Chen-Chan WeiDepartment of Aquatic Sport, University of Taipei, Taipei 11153, Taiwan. tom911072@gmail.com.
Chi-Chang HuangGraduate Institute of Sports Science, National Taiwan Sport University, Taoyuan 33301, Taiwan. john5523@mail.ntsu.edu.tw.
Wen-Lin ChenDepartment of Food Science, Nutrition, and Nutraceutical Biotechnology, Shih Chien University, Taipei 10462, Taiwan. maggieh323@hotmail.com.
Hui-Yu HuangDepartment of Food Science, Nutrition, and Nutraceutical Biotechnology, Shih Chien University, Taipei 10462, Taiwan. maggieh@mail.usc.edu.tw.
Shih Chien University · TWNational Taipei University of Nursing and Health Science · TWNational Taiwan Sport University · TWUniversity of Taipei · TW

Funding

Ministry of Science and Technology in Taiwan MOST 107-2410-H-227-007
6 · The paper itself

Abstract

A triathlon, which consists of swimming, bicycling, and running, is a high-intensity and long-term form of exercise that can cause injuries such as muscular damage, inflammation, oxidative stress, and energy imbalance. Probiotics are thought to play an important role in disease incidence, health promotion, and nutrient metabolism, but only a few studies have focused on physiological adaptations to exercise in sports science. Previous studies indicated that Lactobacillus supplementation could improve oxidative stress and inflammatory responses. We investigate the effects of Lactobacillus plantarum PS128 supplementation on triathletes for possible physiological adaptation. The triathletes were assigned to one of two groups with different exercise intensity stimulations with different time-points to investigate the effects of body compositions, inflammation, oxidative stress, performance, fatigue, and injury-related biochemical indices. L. plantarum PS128 supplementation, combined with training, can significantly alleviate oxidative stress (such as creatine kinase, Thioredoxin, and Myeloperoxidase indices) after a triathlon (p < 0.05). This effect is possibly regulated by a 6⁻13% decrease of indicated pro-inflammation (TNF-α, IL-6, and IL-8) cytokines (p < 0.05) and 55% increase of anti-inflammation (IL-10) cytokines (p < 0.05) after intensive exercise stimulation. In addition, L. plantarum PS128 can also substantially increase 24⁻69% of plasma-branched amino acids (p < 0.05) and elevate exercise performance, as compared to the placebo group (p < 0.05). In conclusion, L. plantarum PS128 may be a potential ergogenic aid for better training management, physiological adaptations to exercise, and health promotion.

Indexed as

AthletesAthletic PerformanceBicyclingHigh-Intensity Interval TrainingHumansInflammationLactiplantibacillus plantarumOxidative StressProbioticsRunningSportsSwimminginflammationL. plantarum PS128oxidative stressperformancetriathlon

Identifiers

PMID30736479
PMCPMC6412901
OpenAlexW2912514651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.