Evidence map›Paper›PMID 30736344›Full record

ArticleMaterials (Basel, Switzerland)2019

Studies on Cell Compatibility, Antibacterial Behavior, and Zeta Potential of Ag-Containing Polydopamine-Coated Bioactive Glass-Ceramic.

Rocío Tejido-Rastrilla, Sara Ferraris, Wolfgang H Goldmann, Alina Grünewald, Rainer Detsch, Giovanni Baldi, Silvia Spriano, Aldo R Boccaccini

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 54 citations in OpenAlex.

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  11. Lanthanides-Substituted Hydroxyapatite/International journal of nanomedicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Rocío Tejido-RastrillaInstitute of Biomaterials, University of Erlangen-Nuremberg, 91058 Erlangen, Germany. rocio.tejido@fau.de.
Sara FerrarisDepartment of Applied Science and Technology, Politecnico di Torino, 10129 Torino, Italy. sara.ferraris@polito.it.
Wolfgang H GoldmannCentre for Medical Physics and Technology, University of Erlangen-Nuremberg, 91052 Erlangen, Germany. wgoldmann@biomed.uni-erlangen.de.
Alina GrünewaldInstitute of Biomaterials, University of Erlangen-Nuremberg, 91058 Erlangen, Germany. alina.gruenewald@fau.de.
Rainer DetschInstitute of Biomaterials, University of Erlangen-Nuremberg, 91058 Erlangen, Germany. rainer.detsch@fau.de.
Giovanni BaldiColorobbia Consulting s.r.l., 50053 Sovigliana Vinci, Florence, Italy. baldig@colorobbia.it.
Silvia SprianoDepartment of Applied Science and Technology, Politecnico di Torino, 10129 Torino, Italy. silvia.spriano@polito.it.
Aldo R BoccacciniInstitute of Biomaterials, University of Erlangen-Nuremberg, 91058 Erlangen, Germany. aldo.boccaccini@ww.uni-erlangen.de.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEPolitecnico di Torino · ITColorobbia (Italy) · IT

Funding

Horizon 2020 Framework Programme 642557
6 · The paper itself

Abstract

Dopamine is a small molecule that mimics the adhesive component (L-DOPA) of marine mussels with a catecholamine structure. Dopamine can spontaneously polymerize to form polydopamine (PDA) in a mild basic environment. PDA binds, in principle, to all types of surfaces and offers a platform for post-modification of surfaces. In this work, a novel Ag-containing polydopamine coating has been developed for the functionalization of bioactive glass-ceramics. In order to study the interactions between the surface of uncoated and coated samples and the environment, we have measured the surface zeta potential. Results confirmed that PDA can interact with the substrate through different chemical groups. A strongly negative surface zeta potential was measured, which is desirable for biocompatibility. The dual function of the material, namely the capability to exhibit bioactive behavior while being antibacterial and not harmful to mammalian cells, was assessed. The biocompatibility of the samples with MG-63 (osteoblast-like) cells was determined, as well as the antibacterial behavior against Gram-positive

Indexed as

antibacterialbioactive glass-ceramicbiocompatibilitycoatingspolydopaminesilver

Identifiers

PMID30736344
PMCPMC6384827
OpenAlexW2914537514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.