Evidence map›Paper›PMID 30735645›Full record

ArticleCell stem cell2019

Human Spermatogonial Stem Cells Scrutinized under the Single-Cell Magnifying Glass.

Kun Tan, Miles F Wilkinson

Abstract readComment
In one paragraph

Article in Cell stem cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Germline stem cells in human.Signal transduction and targeted therapy · 2022
    Review
  6. Article
  7. Review
  8. Article
  9. The Application of Single-Cell RNA Sequencing in Mammalian Meiosis Studies.Frontiers in cell and developmental biology · 2021
    Review
  10. A single-cell view of spermatogonial stem cells.Current opinion in cell biology · 2020
    Review
  11. Transcriptome profiling reveals signaling conditions dictating human spermatogonia fate in vitro.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  12. Article
  13. Review
  14. Xeno-Free Propagation of Spermatogonial Stem Cells from Infant Boys.International journal of molecular sciences · 2019
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Kun TanDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA 92093, USA.
Miles F WilkinsonDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA 92093, USA; Institute of Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: mfwilkinson@ucsd.edu.

Funding

Spermatogonial Stem Cell Establishment and RegulationR01GM119128 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TAN, KUN, WILKINSON, MILES FROME · 2016 to 2025
$3.6M
NIGMS NIH HHS R01 GM119128
6 · The paper itself

Abstract

Spermatogonial stem cells (SSCs) are essential for adult spermatogenesis. Recently, Wang et al. (2018), Guo et al. (2018), and Hermann et al. (2018) used single-cell RNA sequencing to define and molecularly characterize human testicular cell populations, including spermatogonial subsets with characteristics of human SSCs.

Indexed as

SpermatogenesisSpermatogoniaAdultHumansMaleSequence Analysis, RNAStem CellsTestis

Identifiers

PMID30735645
PMCPMC6415922

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.