Evidence map›Paper›PMID 30735120›Full record

ArticleeLife2019

JNK-dependent cell cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress.

Andrea Cosolo, Janhvi Jaiswal, Gábor Csordás, Isabelle Grass, Mirka Uhlirova, Anne-Kathrin Classen

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
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  10. ALDHCells · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Andrea CosoloCenter for Biological Systems Analysis, University of Freiburg, Freiburg, Germany.ORCID 0000-0003-3417-0713
Janhvi JaiswalSpemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Freiburg, Germany.
Gábor CsordásCologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.ORCID 0000-0001-6871-6839
Isabelle GrassFaculty of Biology, Ludwig-Maximilians-University Munich, Munich, Germany.
Mirka UhlirovaCologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.ORCID 0000-0002-5735-8287
Anne-Kathrin ClassenFaculty of Biology, Ludwig-Maximilians-University Munich, Munich, Germany.ORCID 0000-0001-5157-0749
University of Freiburg · DEUniversity of Cologne · DE

Funding

Boehringer Ingelheim Stiftung Plus3 ProgrammeDeutsche Forschungsgemeinschaft CL490-1/1Deutsche Forschungsgemeinschaft EXC-2189 - Project ID 390939984
6 · The paper itself

Abstract

The restoration of homeostasis after tissue damage relies on proper spatial-temporal control of damage-induced apoptosis and compensatory proliferation. In

Indexed as

AnimalsApoptosisCarcinogenesisCell Cycle CheckpointsCell DivisionCell ProliferationCellular SenescenceDrosophila melanogasterG2 Phase Cell Cycle CheckpointsHumansImaginal DiscsJNK Mitogen-Activated Protein KinasesMAP Kinase Signaling SystemStress, PhysiologicalWound HealingJNK Mitogen-Activated Protein Kinasescell biologydevelopmental biologyD. melanogasterG2 arrestinjury-induced apoptosisJNKnon-autonomous overgrowthsenescencetissue damage

Identifiers

PMID30735120
PMCPMC6389326
OpenAlexW2912756259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.