Evidence map›Paper›PMID 30734661›Full record

ArticleTissue engineering. Part A2019

Comparison of Stromal Vascular Fraction and Passaged Adipose-Derived Stromal/Stem Cells as Point-of-Care Agents for Bone Regeneration.

Ethan Nyberg, Ashley Farris, Aine O'Sullivan, Ricardo Rodriguez, Warren Grayson

Registry-linked trialAbstract readComparative Study
In one paragraph

Article in Tissue engineering. Part A, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06705023 (Adipose-derived Regenerative Cells Treatment for Congestive Heart Failure), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06705023 phase2recruitingnot on this mapstarted 2024, after this paper: background citation

Adipose-derived Regenerative Cells Treatment for Congestive Heart Failure

TypeinterventionalSponsorRalf RothoerlRan2024 to 2025Enrolled36ConditionsMyocardial Injury, LV Dysfunction, Coronary Artery Disease, Heart FailureArmsUncultured, autologous, adipose-derived regenerative cells (UA-ADRCs), Continuation of patient's best guideline based medical treatment
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. The Use of Stromal Vascular Fraction in Long Bone Defect Healing in Sheep.Animals : an open access journal from MDPI · 2023
    Article
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  11. Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ethan NybergTranslational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Ashley FarrisTranslational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Aine O'SullivanTranslational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Ricardo RodriguezCosmeticSurg, LLC, Luthersville, Maryland.
Warren GraysonTranslational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Funding

Oxygen-eluting scaffolds for cranial bone regenerationR01DE027957 · NIDCR · JOHNS HOPKINS UNIVERSITY · PI GRAYSON, WARREN L, PATHAK, ARVIND P · 2019 to 2023
$2.4M
NIDCR NIH HHS R01 DE027957
6 · The paper itself

Abstract

Large craniofacial bone defects remain a clinical challenge due to their complex shapes and large volumes. Stem cell-based technologies that deliver osteogenic stem cells have shown remarkable regenerative potential but are hampered by the need for extensive

Indexed as

Point-of-Care SystemsAdipose TissueAdultAnimalsBone RegenerationCalcification, PhysiologicFemaleHindlimbHumansMaleMice, NudeMiddle AgedSkullStem CellsStromal CellsTissue Scaffolds3D printingadipose-derived stromal/stem cellsbone tissue engineeringosseointegrationstromal vascular fraction

Identifiers

PMID30734661
PMCPMC12407092

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.