Evidence map›Paper›PMID 30734613›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2019

Hydroxyl-substituted double Schiff-base condensed 4-piperidone/cyclohexanones as potential anticancer agents with biological evaluation.

Lianshuang Zhang, Qin Chen, Guige Hou, Wei Zhao, Yun Hou

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Recent advances in piperidones as privileged scaffolds for drug discovery and development.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Review
  3. Article
  4. Article
  5. Potential anti-neuroinflammatory NF-кB inhibitors based on 3,4-dihydronaphthalen-1(2Journal of enzyme inhibition and medicinal chemistry · 2020
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lianshuang Zhanga School of Basic Medical Sciences, Binzhou Medical University , Yantai , P. R. China.
Qin Chenb Department of Pharmacy , Taihe County People's Hospital , Taihe , P. R. China.
Guige Houa School of Basic Medical Sciences, Binzhou Medical University , Yantai , P. R. China.
Wei Zhaoa School of Basic Medical Sciences, Binzhou Medical University , Yantai , P. R. China.
Yun Houa School of Basic Medical Sciences, Binzhou Medical University , Yantai , P. R. China.
Binzhou Medical University · CNBinzhou University · CNTaihe Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel hydroxyl-substituted double Schiff-base 4-piperidone/cyclohexanone derivatives, 3a-e, 4a-e, 5a-d, and 6a-c, were synthesized and fully characterized by

Indexed as

AnimalsAntineoplastic AgentsApoptosisCell Line, TumorCell ProliferationCyclohexanonesDose-Response Relationship, DrugDrug Screening Assays, AntitumorFemaleHumansHydroxidesLiver Neoplasms, ExperimentalMiceMice, Inbred BALB CMice, NudeMolecular Docking SimulationAntineoplastic AgentsCyclohexanoneshydroxide ionHydroxidesPiperidonesSchiff Bases3,5-(arylidene)-4-piperidoneanticancer activitycyclohexanoneSchiff-base

Identifiers

PMID30734613
PMCPMC6327999
OpenAlexW2907428894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.