Evidence map›Paper›PMID 30734592›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2019

Synthesis carbonic anhydrase enzyme inhibition and antioxidant activity of novel benzothiazole derivatives incorporating glycine, methionine, alanine, and phenylalanine moieties.

Deniz Üzeroğlu Payaz, F Zehra Küçükbay, Hasan Küçükbay, Andrea Angeli, Claudiu T Supuran

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  6. Benzothiazole derivatives as anticancer agents.Journal of enzyme inhibition and medicinal chemistry · 2020
    Review
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  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Deniz Üzeroğlu Payaza Department of Chemistry, Faculty of Arts and Sciences , İnönü University , Malatya , Turkey.ORCID http://orcid.org/0000-0002-4160-5669
F Zehra Küçükbayb Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy , İnönü University , Malatya , Turkey.ORCID http://orcid.org/0000-0002-5471-3933
Hasan Küçükbaya Department of Chemistry, Faculty of Arts and Sciences , İnönü University , Malatya , Turkey.ORCID http://orcid.org/0000-0002-7180-9486
Andrea Angelic Dipartimento Neurofarba, Sezione Di Scienze Farmaceutiche E Nutraceutiche e Laboratorio Di Chimica Bioinorganica, Universita` Degli Studi Di Firenze , Florence , Italy.ORCID http://orcid.org/0000-0002-1470-7192
Claudiu T Supuranc Dipartimento Neurofarba, Sezione Di Scienze Farmaceutiche E Nutraceutiche e Laboratorio Di Chimica Bioinorganica, Universita` Degli Studi Di Firenze , Florence , Italy.ORCID http://orcid.org/0000-0003-4262-0323
Inonu University · TRUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thirteen novel benzothiazole derivatives incorporating glycine, methionine, alanine, and phenylalanine were synthesised by facile acylation reactions through benzotriazole or DCC mediated reactions and their structures were identified by

Indexed as

AlanineAntioxidantsBenzothiazolesCarbonic Anhydrase InhibitorsCarbonic AnhydrasesDose-Response Relationship, DrugGlycineHumansIsoenzymesMethionineMolecular StructurePhenylalanineStructure-Activity RelationshipAlanineAntioxidantsbenzothiazoleBenzothiazolesCarbonic Anhydrase InhibitorsCarbonic AnhydrasesGlycineIsoenzymesMethioninePhenylalanineBenzothiazole; amino acids; carbonic anhydrase; antioxidant; benzotriazole methodology

Identifiers

PMID30734592
PMCPMC6327993
OpenAlexW2908476444

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.