Evidence map›Paper›PMID 30734388›Full record

Trial reportJournal of magnetic resonance imaging : JMRI2019

Highly-accelerated volumetric brain examination using optimized wave-CAIPI encoding.

Daniel Polak, Stephen Cauley, Susie Y Huang, Maria Gabriela Longo, John Conklin, Berkin Bilgic, Ned Ohringer, Esther Raithel, Peter Bachert, Lawrence L Wald and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of magnetic resonance imaging : JMRI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Group-Patch Joint Compression: Compressing Dynamic BMagnetic resonance in medicine · 2026
    Article
  2. Article
  3. Ultra-fast MRI for dementia diagnosis and treatment eligibility: A prospective study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
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  5. Review
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  11. Review
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  15. Review
  16. Article
  17. Clinical Application of MPRAGE Wave Controlled Aliasing in Parallel Imaging (Wave-CAIPI): A Comparative Study with MPRAGE GRAPPA.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2022
    Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Daniel PolakDepartment of Physics and Astronomy, Heidelberg University, Heidelberg, Germany.
Stephen CauleyDepartment of Radiology, A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Susie Y HuangDepartment of Radiology, A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Maria Gabriela LongoDivision of Neuroradiology, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA.
John ConklinHarvard Medical School, Boston, Massachusetts, USA.
Berkin BilgicDepartment of Radiology, A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Ned OhringerDepartment of Radiology, A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Esther RaithelSiemens Healthcare, Erlangen, Germany.
Peter BachertDepartment of Physics and Astronomy, Heidelberg University, Heidelberg, Germany.
Lawrence L WaldDepartment of Radiology, A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Kawin SetsompopDepartment of Radiology, A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA.

Funding

MRI CORTICOGRAPHY: DEVELOPING NEXT GENERATION MICROSCALE HUMAN CORTEX MRI SCANNERU01EB025162 · NIBIB · UNIVERSITY OF CALIFORNIA BERKELEY · PI FEINBERG, DAVID ALAN, LIU, CHUNLEI · 2017 to 2021
$13.4M
Project 4P41EB015896 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2012 to 2018
$9.8M
Next generation in-vivo diffusion imaging at submillimeter resolutionR01MH116173 · NIMH · STANFORD UNIVERSITY · PI Yogesh Rathi, Kawin Setsompop · 2018 to 2026
$6.2M
fMRI Technologies for Imaging at the Limit of Biological Spatiotemporal Resolution: Administrative SupplementR01EB019437 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI POLIMENI, JONATHAN RIZZO, SETSOMPOP, KAWIN · 2015 to 2024
$5.5M
Rapid MRI acquisition for pediatric low-grade gliomasR01EB020613 · NIBIB · STANFORD UNIVERSITY · PI SETSOMPOP, KAWIN · 2016 to 2019
$2.5M
A Storage Area Network for Structural and Functional Image AnalysisS10RR023401 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI FISCHL, BRUCE · 2009 to 2009
$2.0M
SILICON GRAPHICS PRISM EXTREME 128P/1TBS10RR023043 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI SORENSEN, ALMA GREGORY · 2006 to 2006
$1.5M
Computeserver Structural &Functional Image AnalysisS10RR019307 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI FISCHL, BRUCE · 2004 to 2004
$496k
NCRR NIH HHS S10 RR019307NCRR NIH HHS S10 RR023043NCRR NIH HHS S10 RR023401NIBIB NIH HHS P41 EB015896NIBIB NIH HHS R01 EB019437NIBIB NIH HHS R01 EB020613NIBIB NIH HHS U01 EB025162NIMH NIH HHS R01 MH116173
6 · The paper itself

Abstract

backgroundRapid volumetric imaging protocols could better utilize limited scanner resources. PURPOSE: To develop and validate an optimized 6-minute high-resolution volumetric brain MRI examination using Wave-CAIPI encoding. STUDY TYPE: Prospective. POPULATION/SUBJECTS: Ten healthy subjects and 20 patients with a variety of intracranial pathologies. FIELD STRENGTH/SEQUENCE: At 3 T, MPRAGE, T ASSESSMENT: Extensive simulations were performed to optimize the Wave-CAIPI protocol and minimize both g-factor noise amplification and potential T STATISTICAL TEST: A noninferiority test was used to test whether the diagnostic quality of Wave-CAIPI was noninferior to the GRAPPA acquisition, with a 15% noninferiority margin.

resultsAmong all sequences, Wave-CAIPI achieved negligible g-factor noise amplification (g DATA

conclusionThe proposed volumetric brain exam retained comparable image quality when compared with the much longer conventional protocol. LEVEL OF EVIDENCE: 2 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2019;50:961-974.

Indexed as

AdultAgedAged, 80 and overArtifactsBrainBrain DiseasesFemaleHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedOrgan SizeProspective StudiesReproducibility of ResultsSingle-Blind Method

Identifiers

PMID30734388
PMCPMC6687581

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.