Evidence map›Paper›PMID 30734167›Full record

ArticleClinical and experimental nephrology2019

The clinical characteristics of Chinese patients with unilateral renal agenesis.

Qian Xu, Hangdi Wu, Lihan Zhou, Jingyuan Xie, Wen Zhang, Haijin Yu, Weiming Wang, Ying Qian, Qianying Zhang, Panpan Qiao and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical and experimental nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Retrospective evaluation of children with unilateral renal agenesis.Pediatric nephrology (Berlin, Germany) · 2021
    Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Qian XuNephrology Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hangdi WuNephrology Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lihan ZhouNephrology Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jingyuan XieNephrology Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wen ZhangNephrology Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Haijin YuNephrology Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Weiming WangNephrology Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ying QianNephrology Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Qianying ZhangNephrology Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Panpan QiaoNephrology Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yonghua TangRadiology Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiaonong ChenNephrology Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhaohui WangNephrology Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. wzhaohui2001@163.com.
Nan ChenNephrology Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Funding

National Natural Science Foundation of China 81170634National Natural Science Foundation of China 81370015National Natural Science Foundation of China 81570598
6 · The paper itself

Abstract

backgroundWe aimed to investigate the clinical characteristics of Chinese patients with unilateral renal agenesis.

methodsWe enrolled patients with unilateral renal agenesis diagnosed radiologically at the Department of Nephrology from January 2008 to January 2016. Patients with a solitary kidney due to nephrectomy or renal atrophy due to secondary factors were excluded. Clinical data were recorded and analyzed.

resultsIn this study, 118 Chinese patients with unilateral renal agenesis were recruited, and the gender ratio (male/female) was 1.11:1. A total of 14 (11.9%) patients had additional abnormalities, 15 (12.7%) had a family history, and 30 (25.4%) presented with renal insufficiency. Kidney length, serum creatinine level and estimated glomerular filtration rate were significantly different between patients with and without family history (P < 0.05, respectively). Gender showed a significant difference between patients with and without other abnormalities. Kidney length and the incidence of proteinuria, hematuria, hypertension, and hyperuricemia were significantly different between patients with and without renal insufficiency. Logistic regression analysis revealed that family history was associated with severe renal failure (OR = 7.11, 95% CI 1.52-33.25).

conclusionRenal insufficiency is common in patients with unilateral renal agenesis. Patients with renal insufficiency have shorter kidney lengths and a higher incidence of proteinuria, hypertension, hematuria, and hyperuricemia. Family history is considered a risk factor for severe renal failure.

Indexed as

AdolescentAdultAgedChinaFemaleHumansMaleMiddle AgedRenal InsufficiencySolitary KidneyYoung AdultChinese populationClinical characteristicsRenal insufficiencyUnilateral renal agenesis

Identifiers

PMID30734167

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