Evidence map›Paper›PMID 30734116›Full record

ArticleClinical rheumatology2019

The clinical spectrum of Henoch-Schönlein purpura in children: a single-center study.

Şerife Gül Karadağ, Ayşe Tanatar, Hafize Emine Sönmez, Figen Çakmak, Aysel Kıyak, Sevgi Yavuz, Mustafa Çakan, Nuray Aktay Ayaz

Abstract read
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In one paragraph

Article in Clinical rheumatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  18. [Risk factors associated with different types of Henoch-Schönlein purpura in Tibetan patients at high altitude].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Şerife Gül KaradağKanuni Sultan Süleyman Research and Training Hospital, Department of Pediatric Rheumatology, University of Health Science, No: 46/1, Kucukcekmece, 34303, Istanbul, Turkey.
Ayşe TanatarKanuni Sultan Süleyman Research and Training Hospital, Department of Pediatric Rheumatology, University of Health Science, No: 46/1, Kucukcekmece, 34303, Istanbul, Turkey.
Hafize Emine SönmezKanuni Sultan Süleyman Research and Training Hospital, Department of Pediatric Rheumatology, University of Health Science, No: 46/1, Kucukcekmece, 34303, Istanbul, Turkey.
Figen ÇakmakKanuni Sultan Süleyman Research and Training Hospital, Department of Pediatric Rheumatology, University of Health Science, No: 46/1, Kucukcekmece, 34303, Istanbul, Turkey.
Aysel KıyakKanuni Sultan Süleyman Research and Training Hospital, Department of Pediatric Nephrology, University of Health Science, Istanbul, Turkey.
Sevgi YavuzKanuni Sultan Süleyman Research and Training Hospital, Department of Pediatric Nephrology, University of Health Science, Istanbul, Turkey.
Mustafa ÇakanKanuni Sultan Süleyman Research and Training Hospital, Department of Pediatric Rheumatology, University of Health Science, No: 46/1, Kucukcekmece, 34303, Istanbul, Turkey.
Nuray Aktay AyazKanuni Sultan Süleyman Research and Training Hospital, Department of Pediatric Rheumatology, University of Health Science, No: 46/1, Kucukcekmece, 34303, Istanbul, Turkey. nurayaktay@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesHenoch-Schönlein purpura (HSP) is the most common vasculitis of children. The aim of this study is to evaluate the demographic and clinic findings of patients with HSP and also to determine predictive factors for assessing the development of gastrointestinal system (GIS) and renal involvement.

methodsThis study was performed prospectively among children with HSP who are under 18 years of age and being followed-up in the Pediatric Rheumatology Unit of Health Sciences University Kanuni Sultan Süleyman Training and Research Hospital between January 2016 and January 2018.

resultsA total of 265 patients, 137 boys (51.7%) and 128 girls (48.3%), were involved to the study. The mean ± standard deviation of age at the diagnosis was 7.5 ± 3.2. The most common disease onset season was spring (31.7%). The rate of arthritis, GIS involvement, and renal involvement were 54%, 51.3%, and 29.1%, respectively. GIS bleeding was more frequent in males than females (p = 0.007). Boys over 7 years of age had significantly more common GIS bleeding (p = 0.04). Intussusception, relapse, and serious GIS involvement requiring hospitalization and steroid treatment were highly associated with severe renal involvement.

conclusionsWe demonstrated that patients suffering intussusception, relapse, and serious GIS involvement or requiring hospitalization and steroid treatment had tendency to present with severe renal involvement. Therefore, these patients should be followed up carefully for not overlooking renal involvement of HSP.

Indexed as

Abdominal PainArthritisChildChild, PreschoolFemaleGastrointestinal HemorrhageHospitalizationHumansIgA VasculitisIntussusceptionKidney DiseasesMaleProspective StudiesRecurrenceSteroidsTurkeySteroidsChildrenGastrointestinal system involvementHenoch–Schönlein purpuraIntussusceptionRelapseRenal involvement

Identifiers

PMID30734116

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.