Evidence map›Paper›PMID 30734010›Full record

SynthesisBJS open2019

Systematic review of definitions and outcome measures for return of bowel function after gastrointestinal surgery.

S J Chapman, G Thorpe, A E Vallance, D P Harji, M J Lee, N S Fearnhead, Association of Coloproctology of Great Britain and Ireland Gastrointestinal Recovery Group

Registry-linked trialOpen access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BJS open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07144969 (Comparison of the Effect of Chewing Gum and Honey on Postoperative Recovery and Complications in Ileostomy Reversal), which is not on this map. Cited by 38 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 10 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07144969 nacompletednot on this mapstarted 2024, after this paper: background citation

Comparison of the Effect of Chewing Gum and Honey on Postoperative Recovery and Complications in Ileostomy Reversal

TypeinterventionalSponsorMayo Hospital LahoreRan2024 to 2024Enrolled60ConditionsIleostomy Closure, Gum Chewing, Honey, Postoperative RecoveryArmsHoney, gum chewing
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 10 syntheses or guidelines pooled it, 79 citations in OpenAlex.

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  8. The Impact of Sham Feeding with Chewing Gum on Postoperative Ileus Following Colorectal Surgery: a Meta-Analysis of Randomised Controlled Trials.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

S J ChapmanLeeds Institute of Biomedical and Clinical Sciences University of Leeds Leeds UK.ORCID 0000-0003-2413-5690
G ThorpeFaculty of Medicine and Health Sciences University of East Anglia Norwich UK.
A E VallanceRoyal Devon and Exeter Hospital Exeter UK.
D P HarjiNewcastle Centre for Bowel Disease, Royal Victoria Infirmary Newcastle upon Tyne UK.ORCID 0000-0002-8493-3312
M J LeeNorthern General Hospital, Sheffield Teaching Hospitals NHS Foundation Trust Sheffield UK.ORCID 0000-0001-9971-1635
N S FearnheadDepartment of Colorectal Surgery Cambridge University Hospitals NHS Foundation Trust Cambridge UK.
Association of Coloproctology of Great Britain and Ireland Gastrointestinal Recovery Group
Cambridge University Hospitals NHS Foundation Trust · GBNorthern General Hospital · GBRoyal Devon and Exeter Hospital · GBRoyal Victoria Infirmary · GBUniversity of East Anglia · GBUniversity of Leeds · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ileus is common after gastrointestinal surgery and has been identified as a research priority. Several issues have limited previous research, including a widely accepted definition and agreed outcome measure. This review is the first stage in the development of a core outcome set for the return of bowel function after gastrointestinal surgery. It aims to characterize the extent of variation in current outcome reporting. Methods: A systematic search of MEDLINE, Embase, CINAHL (Cumulative Index to Nursing and Allied Health Literature) and the Cochrane Library was performed for 1990-2017. RCTs of adults undergoing gastrointestinal surgery, including at least one reported measure relating to return of bowel function, were eligible. Trial registries were searched across the same period for ongoing and completed (but not published) RCTs. Definitions of ileus and outcome measures describing the return of bowel function were extracted. Results: Of 5670 manuscripts screened, 215 (reporting 217 RCTs) were eligible. Most RCTs involved patients undergoing colorectal surgery (161 of 217, 74·2 per cent). A total of 784 outcomes were identified across all published RCTs, comprising 73 measures (clinical: 63, 86 per cent; radiological: 6, 8 per cent; physiological: 4, 5 per cent). The most commonly reported outcome measure was 'time to first passage of flatus' (140 of 217, 64·5 per cent). The outcomes 'ileus' and 'prolonged ileus' were defined infrequently and variably. Conclusion: Outcome reporting for the return of bowel function after gastrointestinal surgery is variable and not fit for purpose. An agreed core outcome set will improve the consistency, reliability and clinical value of future studies.

Indexed as

Recovery of FunctionDefecationDigestive System Surgical ProceduresGastrointestinal MotilityGastrointestinal TractHumansIleusOutcome Assessment, Health CarePostoperative ComplicationsRandomized Controlled Trials as TopicTerminology as Topic

Identifiers

PMID30734010
PMCPMC6354191
OpenAlexW2895443777

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.