Evidence map›Paper›PMID 30733731›Full record

ReviewJournal, genetic engineering & biotechnology2018

Quorum sensing intervened bacterial signaling: Pursuit of its cognizance and repression.

Kayeen Vadakkan, Abbas Alam Choudhury, Ramya Gunasekaran, Janarthanam Hemapriya, Selvaraj Vijayanand

Abstract readReview
In one paragraph

Review in Journal, genetic engineering & biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Exploration of anti-quorum sensing properties of eicosyl heptafluorobutyrate against a clinical strain of Pseudomonas aeruginosa.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Anti-Biofilm and Anti-Quorum-Sensing Activity ofPharmaceuticals (Basel, Switzerland) · 2024
    Article
  9. Regulation of virulence inFrontiers in microbiology · 2024
    Review
  10. Microbial Extracellular Vesicles in Host-Microbiota Interactions.Results and problems in cell differentiation · 2024
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. SdiA Enhanced the Drug Resistance ofFrontiers in microbiology · 2022
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kayeen VadakkanBioresource Technology Lab, Department of Biotechnology, Thiruvalluvar University, Vellore, TN 632115, India.
Abbas Alam ChoudhuryBioresource Technology Lab, Department of Biotechnology, Thiruvalluvar University, Vellore, TN 632115, India.
Ramya GunasekaranBioresource Technology Lab, Department of Biotechnology, Thiruvalluvar University, Vellore, TN 632115, India.
Janarthanam HemapriyaDepartment of Microbiology, DKM College for Women, Vellore, TN 632001, India.
Selvaraj VijayanandBioresource Technology Lab, Department of Biotechnology, Thiruvalluvar University, Vellore, TN 632115, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria communicate within a system by means of a density dependent mechanism known as quorum sensing which regulate the metabolic and behavioral activities of a bacterial community. This sort of interaction occurs through a dialect of chemical signals called as autoinducers synthesized by bacteria. Bacterial quorum sensing occurs through various complex pathways depending upon specious diversity. Therefore the cognizance of quorum sensing mechanism will enable the regulation and thereby constrain bacterial communication. Inhibition strategies of quorum sensing are collectively called as quorum quenching; through which bacteria are incapacitated of its interaction with each other. Many virulence mechanism such as sporulation, biofilm formation, toxin production can be blocked by quorum quenching. Usually quorum quenching mechanisms can be broadly classified into enzymatic methods and non-enzymatic methods. Substantial understanding of bacterial communication and its inhibition enhances the development of novel antibacterial therapeutic drugs. In this review we have discussed the types and mechanisms of quorum sensing and various methods to inhibit and regulate density dependent bacterial communication.

Indexed as

Antibacterial agentsAutoinducersQuorum quenchingQuorum sensing

Identifiers

PMID30733731
PMCPMC6353778

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.