Evidence map›Paper›PMID 30733729›Full record

ReviewFrontiers in plant science2018

Vitamin C Content in Fruits: Biosynthesis and Regulation.

Mario Fenech, Iraida Amaya, Victoriano Valpuesta, Miguel A Botella

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in plant science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers.

0numbers the graph read from it
0cells of the map it votes in
114citing papers in PubMed
45.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

114 citing papers in PubMed, 344 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Natural novel vitamin C derivative, 2-Chinese herbal medicines · 2026
    Review
  11. Physicochemical Changes and Antioxidant Metabolism ofMolecules (Basel, Switzerland) · 2025
    Article
  12. Endophyte-Mediated Reinforcement of Morpho-Physiology ofIndian journal of microbiology · 2025
    Article
  13. Biofortification of potato nutrition.Journal of advanced research · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Environmental conditions and nutritional quality of vegetables in protected cultivation.Comprehensive reviews in food science and food safety · 2025
    Review
  19. Article
  20. Article

54 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mario FenechDepartamento de Biología Molecular y Bioquímica, Instituto de Hortofruticultura Subtropical y Mediterránea (IHSM), Consejo Superior de Investigaciones Científicas, Universidad de Málaga, Málaga, Spain.
Iraida AmayaInstituto Andaluz de Investigación y Formación Agraria y Pesquera, Area de Genómica y Biotecnología, Centro de Málaga, Spain.
Victoriano ValpuestaDepartamento de Biología Molecular y Bioquímica, Instituto de Hortofruticultura Subtropical y Mediterránea (IHSM), Consejo Superior de Investigaciones Científicas, Universidad de Málaga, Málaga, Spain.
Miguel A BotellaDepartamento de Biología Molecular y Bioquímica, Instituto de Hortofruticultura Subtropical y Mediterránea (IHSM), Consejo Superior de Investigaciones Científicas, Universidad de Málaga, Málaga, Spain.
Consejo Superior de Investigaciones Científicas · ESAndalusian Institute of Agricultural and Fisheries Research and Training · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Throughout evolution, a number of animals including humans have lost the ability to synthesize ascorbic acid (ascorbate, vitamin C), an essential molecule in the physiology of animals and plants. In addition to its main role as an antioxidant and cofactor in redox reactions, recent reports have shown an important role of ascorbate in the activation of epigenetic mechanisms controlling cell differentiation, dysregulation of which can lead to the development of certain types of cancer. Although fruits and vegetables constitute the main source of ascorbate in the human diet, rising its content has not been a major breeding goal, despite the large inter- and intraspecific variation in ascorbate content in fruit crops. Nowadays, there is an increasing interest to boost ascorbate content, not only to improve fruit quality but also to generate crops with elevated stress tolerance. Several attempts to increase ascorbate in fruits have achieved fairly good results but, in some cases, detrimental effects in fruit development also occur, likely due to the interaction between the biosynthesis of ascorbate and components of the cell wall. Plants synthesize ascorbate

Indexed as

ascorbic acidbiosynthesiscell wallfruitregulationvitamin C

Identifiers

PMID30733729
PMCPMC6353827
OpenAlexW2912485197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.