Evidence map›Paper›PMID 30733702›Full record

ArticleFrontiers in neurology2019

Plasma Calcitonin Gene-Related Peptide: A Potential Biomarker for Diagnosis and Therapeutic Responses in Pediatric Migraine.

Pi-Chuan Fan, Ping-Hung Kuo, Ming Tatt Lee, Shu-Hui Chang, Lih-Chu Chiou

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04473976 (Plasma Levels of CGRP and Expression of Specific microRNAs in Blood Cells of Episodic and Chronic Migraine Subjects), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04473976 completednot on this map

Plasma Levels of CGRP and Expression of Specific microRNAs in Blood Cells of Episodic and Chronic Migraine Subjects: Toward the Identification of a Panel of Peripheral Biomarkers of Migraine?

TypeobservationalSponsorIRCCS National Neurological Institute "C. Mondino" FoundationRan2017 to 2019Enrolled55ConditionsMigraine
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Migraine in children and adolescents.Developmental medicine and child neurology · 2026
    Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Biomarkers and Endophenotypes of Post-traumatic Headaches.Current pain and headache reports · 2024
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. CGRP measurements in human plasma - a methodological study.Cephalalgia : an international journal of headache · 2021
    Article
  17. Review
  18. α6GABANeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Pi-Chuan FanDepartment of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.
Ping-Hung KuoDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Ming Tatt LeeGraduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Shu-Hui ChangDepartment of Epidemiology, College of Public Health, National Taiwan University, Taipei, Taiwan.
Lih-Chu ChiouClinical Center for Neuroscience and Behavior, National Taiwan University Hospital, Taipei, Taiwan.
National Taiwan University · TWNational Taiwan University Hospital · TWChina Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anti-migraine drugscalcitonin gene-related peptidepediatric migraineplasma biomarkertopiramate

Identifiers

PMID30733702
PMCPMC6353836
OpenAlexW2911244382

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.