Evidence map›Paper›PMID 30733684›Full record

ArticleFrontiers in physiology2018

Methylation in MIRLET7A3 Gene Induces the Expression of IGF-II and Its mRNA Binding Proteins IGF2BP-2 and 3 in Hepatocellular Carcinoma.

Amr A Waly, Nada El-Ekiaby, Reem A Assal, Mohamed M Abdelrahman, Karim A Hosny, Hend M El Tayebi, Gamal Esmat, Kai Breuhahn, Ahmed I Abdelaziz

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. IMPlications of IMP2 in RNA Biology and Disease.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. IGF2BPs as novel mGenes & diseases · 2024
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. The Curious Case of the HepG2 Cell Line: 40 Years of Expertise.International journal of molecular sciences · 2021
    Review
  16. Review
  17. NCell proliferation · 2020
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Amr A WalyThe Molecular Pathology Research Group, German University in Cairo, Cairo, Egypt.
Nada El-EkiabySchool of Medicine, Newgiza University, Cairo, Egypt.
Reem A AssalThe Molecular Pathology Research Group, German University in Cairo, Cairo, Egypt.
Mohamed M AbdelrahmanThe Molecular Pathology Research Group, German University in Cairo, Cairo, Egypt.
Karim A HosnyDepartment of General Surgery, Faculty of Medicine, Cairo University, Cairo, Egypt.
Hend M El TayebiThe Molecular Pathology Research Group, German University in Cairo, Cairo, Egypt.
Gamal EsmatDepartment of Endemic Medicine and Hepatology, Cairo University, Cairo, Egypt.
Kai BreuhahnMolecular Hepatopathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Ahmed I AbdelazizThe Molecular Pathology Research Group, German University in Cairo, Cairo, Egypt.
German University in Cairo · EGCairo University · EGHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

miR-let-7a is a tumor suppressor miRNA with reduced expression in most cancers. Methylation of

Indexed as

HCCIGF2BPIGF-IImethylationmiR-let-7a

Identifiers

PMID30733684
PMCPMC6353855
OpenAlexW2912566932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.