Evidence map›Paper›PMID 30733672›Full record

ArticleFrontiers in behavioral neuroscience2019

Visual Contrast Modulates Operant Learning Responses in Larval Zebrafish.

Wenbin Yang, Yutong Meng, Danyang Li, Quan Wen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in behavioral neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. A comparative analysis ofFrontiers in behavioral neuroscience · 2022
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wenbin YangHefei National Laboratory for Physical Sciences at the Microscale, Center for Integrative Imaging, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Yutong MengHefei National Laboratory for Physical Sciences at the Microscale, Center for Integrative Imaging, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Danyang LiHefei National Laboratory for Physical Sciences at the Microscale, Center for Integrative Imaging, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Quan WenHefei National Laboratory for Physical Sciences at the Microscale, Center for Integrative Imaging, School of Life Sciences, University of Science and Technology of China, Hefei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The larval zebrafish is a promising vertebrate model organism to study neural mechanisms underlying learning and memory due to its small brain and rich behavioral repertoire. Here, we report on a high-throughput operant conditioning system for zebrafish larvae, which can simultaneously train 12 fish to associate a visual conditioned pattern with electroshocks. We find that the learning responses can be enhanced by the visual contrast, not the spatial features of the conditioned patterns, highlighted by several behavioral metrics. By further characterizing the learning curves as well as memory extinction, we demonstrate that the percentage of learners and the memory length increase as the conditioned pattern becomes darker. Finally, little difference in operant learning responses was found between AB wild-type fish and

Indexed as

automated image analysisbehavioral neurosciencehigh-throughput imaginglearningvisionzebrafish larvae

Identifiers

PMID30733672
PMCPMC6353835

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.