Evidence map›Paper›PMID 30733471›Full record

ArticleScientific reports2019

Genome analysis of a thermophilic exopolysaccharide-producing bacterium - Geobacillus sp. WSUCF1.

Jia Wang, Kian Mau Goh, David R Salem, Rajesh K Sani

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
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  5. Production and biological activities of exopolysaccharides synthesized by thermophilic bacilli isolated from hot springs in Türkiye.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
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  11. Review
  12. Polysaccharide-Based Transdermal Drug Delivery.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  13. Article
  14. Article
  15. Genome Annotation of Poly(lactic acid) DegradingInternational journal of molecular sciences · 2021
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Jia WangDepartment of Chemical and Biological Engineering, South Dakota School of Mines and Technology, Rapid City, SD, 57701, USA.
Kian Mau GohFaculty of Science, Universiti Teknologi Malaysia, Skudai, Johor, 81300, Malaysia.ORCID 0000-0002-2839-8722
David R SalemDepartment of Chemical and Biological Engineering, South Dakota School of Mines and Technology, Rapid City, SD, 57701, USA. David.Salem@sdsmt.edu.
Rajesh K SaniDepartment of Chemical and Biological Engineering, South Dakota School of Mines and Technology, Rapid City, SD, 57701, USA. Rajesh.Sani@sdsmt.edu.
South Dakota School of Mines and Technology · USUniversity of Technology Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Geobacillus sp. WSUCF1 is a Gram-positive, spore-forming, aerobic and thermophilic bacterium, isolated from a soil sample obtained from a compost facility. Strain WSUCF1 demonstrated EPS producing capability using different sugars as the carbon source. The whole-genome analysis of WSUCF1 was performed to disclose the essential genes correlated with nucleotide sugar precursor biosynthesis, assembly of monosaccharide units, export of the polysaccharide chain, and regulation of EPS production. Both the biosynthesis pathway and export mechanism of EPS were proposed based on functional annotation. Additionally, the genome description of strain WSUCF1 suggests sophisticated systems for its adaptation under thermophilic conditions. The presence of genes associated with CRISPR-Cas system, quorum quenching lactonase, polyketide synthesis and arsenic resistance makes this strain a potential candidate for various applications in biotechnology and biomedicine. The present study indicates that strain WSUCF1 has promise as a thermophilic EPS producer for a broad range of industrial applications. To the best of our knowledge, this is the first report on genome analysis of a thermophilic Geobacillus species focusing on its EPS biosynthesis and transportation, which will likely pave the way for both enhanced yield and tailor-made EPS production by thermophilic bacteria.

Indexed as

GenomicsTemperatureBiotechnologyGeobacillusPolysaccharides, BacterialStress, PhysiologicalPolysaccharides, Bacterial

Identifiers

PMID30733471
PMCPMC6367360
OpenAlexW2922355460

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.