Evidence map›Paper›PMID 30733269›Full record

ArticleHaematologica2019

Long-term outcome after allogeneic hematopoietic cell transplantation for myelofibrosis.

Marie Robin, Liesbeth C de Wreede, Christine Wolschke, Johannes Schetelig, Diderik-Jan Eikema, Maria Teresa Van Lint, Nina Simone Knelange, Dietrich Beelen, Arne Brecht, Dietger Niederwieser and 17 more

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
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  7. Are transplant indications changing for myelofibrosis?Hematology. American Society of Hematology. Education Program · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 20 institutions in 10 countries.

Marie RobinHôpital Saint-Louis, APHP, Université Paris 7, Paris, France marie.robin@aphp.fr.
Liesbeth C de WreedeDepartment of Biomedical Data Sciences, LUMC, Leiden, the Netherlands and DKMS CTU, Dresden, Germany.
Christine WolschkeUniversity Hospital Eppendorf, Hamburg, Germany.
Johannes ScheteligMedizinische Klinik und Poliklinik I, Universitätsklinikum Dresden, Dresden, Germany.
Diderik-Jan EikemaEBMT Statistical Unit, Leiden, the Netherlands.
Maria Teresa Van LintOspedale San Martino, Genova, Italy.
Nina Simone KnelangeEBMT Data Office, Leiden, the Netherlands.
Dietrich BeelenUniversity Hospital, Essen, Germany.
Arne BrechtHelios HSK Wiesbaden, Wiesbaden, Germany.
Dietger NiederwieserUniversity Hospital Leipzig, Leipzig, Germany.
Antonin VitekInstitute of Hematology and Blood Transfusion, Prague, Czech Republic.
Wolfgang BethgeUniversität Tübingen, Tübingen, Germany.
Renate ArnoldCharité Universitätsmedizin Berlin, Berlin, Germany.
Jürgen FinkeDivision of Medicine I, Hematology, Oncology and Stem Cell Transplantation, University of Freiburg, Freiburg, Germany.
Liisa VolinHUCH Comprehensive Cancer Center, Helsinki, Finland.
Ibrahim Yakoub-AghaCHU de Lille, INSERM U995, Lille, France.
Arnon NaglerChaim Sheba Medical Center, Tel-Hashomer, Israel.
Xavier PoiréCliniques Universitaires St. Luc, Brussels, Belgium.
Hermann EinseleDepartment of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.
Patrice ChevallierCHU Nantes, Nantes, France.
Ernst HollerUniversity Regensburg, Regensburg, Germany.
Per LjungmanKarolinska University Hospital, Stockholm, Sweden.
Stephen RobinsonBristol Oncology Centre, Bristol, UK.
Alekxandar RadujkovicUniversity of Heidelberg, Heidelberg, Germany.
Donal McLornanComprehensive Cancer Centre, Department of Haematology, Kings College, London, UK.
Yves ChalandonHôpitaux Universitaires de Genève and Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Nicolaus KrögerUniversity Hospital Eppendorf, Hamburg, Germany.
European Society for Blood and Marrow Transplantation · NLAt Bristol · GBCentre Hospitalier Universitaire de Lille · FRCentre Hospitalier Universitaire de Nantes · FRCharité - Universitätsmedizin Berlin · DECliniques Universitaires Saint-Luc · BEEssen University Hospital · DEHeidelberg University · DEInstitute of Haematology and Blood Transfusion · CZKarolinska University Hospital · SEKing's College London · GBOspedale Policlinico San Martino · ITSheba Medical Center · ILTU Dresden · DEUniversität Hamburg · DEUniversitätsklinikum Würzburg · DEUniversité Paris Cité · FRUniversity Hospital Leipzig · DEUniversity Medical Center Hamburg-Eppendorf · DEUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allogeneic hematopoietic stem cell transplant remains the only curative treatment for myelofibrosis. Most post-transplantation events occur during the first two years and hence we aimed to analyze the outcome of 2-year disease-free survivors. A total of 1055 patients with myelofibrosis transplanted between 1995 and 2014 and registered in the registry of the European Society for Blood and Marrow Transplantation were included. Survival was compared to the matched general population to determine excess mortality and the risk factors that are associated. In the 2-year survivors, disease-free survival was 64% (60-68%) and overall survival was 74% (71-78%) at ten years; results were better in younger individuals and in women. Excess mortality was 14% (8-21%) in patients aged <45 years and 33% (13-53%) in patients aged ≥65 years. The main cause of death was relapse of the primary disease. Graft-

Indexed as

Hematopoietic Stem Cell TransplantationAdultAgedDisease-Free SurvivalFemaleGraft vs Host DiseaseHumansMaleMiddle AgedMultivariate AnalysisNeoplasm Recurrence, LocalPrimary MyelofibrosisRegistriesRemission InductionRisk FactorsTransplantation, Homologous

Identifiers

PMID30733269
PMCPMC6717573
OpenAlexW2913811147

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.