Evidence map›Paper›PMID 30733248›Full record

ArticleBMJ case reports2019

Arterial thrombosis as primary presentation of endogenous Cushing's syndrome.

Vijay Alexander, Maria Koshy, Riddhi Dasgupta, Ronald Albert Carey

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Unusual infections and thrombotic events in Cushing's syndrome.Journal of endocrinological investigation · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Vijay AlexanderDepartment of Internal Medicine, Christian Medical College, Vellore, Tamil Nadu, India.
Maria KoshyDepartment of Internal Medicine, Christian Medical College, Vellore, Tamil Nadu, India.
Riddhi DasguptaDepartment of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, Tamil Nadu, India.
Ronald Albert CareyDepartment of Internal Medicine, Christian Medical College, Vellore, Tamil Nadu, India.
Christian Medical College · INChristian Medical College & Hospital · INYahoo (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cushing's syndrome is known to present with a characteristic set of clinical manifestations and complications, well described in literature. However, hypercoagulability remains an under recognised entity in Cushing's syndrome. A 31-year-old woman from Southern India presented with history of fever, left upper quadrant pain and progressive breathing difficulty for 3 weeks. Clinical examination revealed discriminatory features of Cushing's syndrome. Laboratory investigations showed biochemical features of endogenous ACTH-dependent Cushing's syndrome. Imaging of the abdomen revealed splenic collection, left-sided empyema and extensive arterial thrombosis. Gadolinium enhanced dynamic MRI of the pituitary gland revealed no evidence of an adenoma while a Ga-68 DOTATATE positron emission tomography CT scan ruled out an ectopic Cushing's. A diagnosis of endogenous Cushing's syndrome causing a prothrombotic state with extensive arterial thrombosis was made. She was initiated on oral anticoagulation and oral ketoconazole for medical adrenal suppression. She subsequently underwent bilateral adrenalectomy and was well at follow-up.

Indexed as

Adrenocorticotropic HormoneAdultAnticoagulantsAortic DiseasesCeliac ArteryComputed Tomography AngiographyCushing SyndromeFemaleHepatic ArteryHumansHydrocortisoneInfarctionKetoconazoleKidney DiseasesMesenteric Artery, SuperiorSplenic ArteryAdrenocorticotropic HormoneAnticoagulantsHydrocortisoneKetoconazolemedical managementpituitary disordersvenous thromboembolism

Identifiers

PMID30733248
PMCPMC6381946
OpenAlexW2912982315

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.