Evidence map›Paper›PMID 30733149›Full record

ArticleNeuron2019

A Selectivity Filter Gate Controls Voltage-Gated Calcium Channel Calcium-Dependent Inactivation.

Fayal Abderemane-Ali, Felix Findeisen, Nathan D Rossen, Daniel L Minor

Open access · bronzeAbstract read
In one paragraph

Article in Neuron, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Deciphering CaProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Inactivation of CaV1 and CaV2 channels.The Journal of general physiology · 2025
    Review
  7. Review
  8. Presynaptic neurons self-tune by inversely coupling neurotransmitter release with the abundance of CaV2 voltage-gated CaProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. EMC chaperone-CaNature · 2023
    Article
  13. Regulation of Cardiac Cav1.2 Channels by Calmodulin.International journal of molecular sciences · 2023
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. CaThe Journal of biological chemistry · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Fayal Abderemane-AliCardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 93858-2330, USA.
Felix FindeisenCardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 93858-2330, USA.
Nathan D RossenCardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 93858-2330, USA.
Daniel L MinorCardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 93858-2330, USA; Departments of Biochemistry and Biophysics, and Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 93858-2330, USA; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, CA 93858-2330, USA; Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA 93858-2330, USA; Molecular Biophysics and Integrated Bio-imaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. Electronic address: daniel.minor@ucsf.edu.
University of California, San Francisco · USQB3 · US

Funding

Structure and function of voltage-gated calcium channelsR01HL080050 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DANIEL L MINOR · 2005 to 2026
$9.8M
NHLBI NIH HHS R01 HL080050
6 · The paper itself

Abstract

Calcium-dependent inactivation (CDI) is a fundamental autoregulatory mechanism in Ca

Indexed as

AnimalsAspartic AcidCalciumCalcium Channels, L-TypeCalcium Channels, N-TypeHEK293 CellsHumansIon Channel GatingMutationOocytesPatch-Clamp TechniquesXenopus laevisAspartic AcidCalciumCalcium Channels, L-TypeCalcium Channels, N-TypeL-type calcium channel alpha(1C)calcium-dependent inactivationCa(V)1.2Ca(V)1.3Ca(V)2.1electrophysiologyselectivity filtervoltage-gated calcium channelvoltage-gated ion channel

Identifiers

PMID30733149
PMCPMC8878153
OpenAlexW2914346470

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.