Evidence map›Paper›PMID 30733043›Full record

ReviewPsychosomatics

Psychiatric Care in Hematopoietic Stem Cell Transplantation.

Zev M Nakamura, Rebekah P Nash, Laura J Quillen, Daniel R Richardson, Rebecca C McCall, Eliza M Park

Open access · greenAbstract readReview
In one paragraph

Review in Psychosomatics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 37 citations in OpenAlex.

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  4. Predictive risk model of mild cognitive impairment in patients with malignant haematological diseases after haematopoietic stem cell transplantation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zev M NakamuraDepartment of Psychiatry, University of North Carolina - Chapel Hill, Chapel Hill, NC. Electronic address: zev.nakamura@unchealth.unc.edu.
Rebekah P NashDepartment of Psychiatry, University of North Carolina - Chapel Hill, Chapel Hill, NC.
Laura J QuillenDepartment of Psychiatry, University of North Carolina - Chapel Hill, Chapel Hill, NC.
Daniel R RichardsonLineberger Comprehensive Cancer Center, University of North Carolina - Chapel Hill, Chapel Hill, NC; The Cecil G. Sheps Center for Health Services Research, University of North Carolina - Chapel Hill, Chapel Hill, NC.
Rebecca C McCallHealth Sciences Library, University of North Carolina - Chapel Hill, Chapel Hill, NC.
Eliza M ParkDepartment of Psychiatry, University of North Carolina - Chapel Hill, Chapel Hill, NC; Lineberger Comprehensive Cancer Center, University of North Carolina - Chapel Hill, Chapel Hill, NC; Department of Medicine, University of North Carolina - Chapel Hill, Chapel Hill, NC.
University of North Carolina at Chapel Hill · US

Funding

UNC-CH TRAINING PROGRAM IN HEALTH SERVICES RESEARCHT32HS000032 · AHRQ · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HOLMES, GEORGE M · 1989 to 2024
$8.2M
A Psychosocial Intervention to Improve Outcomes for Parents with Advanced CancerK07CA218167 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PARK, ELIZA MYUNG · 2017 to 2021
$884k
AHRQ HHS T32 HS000032NCI NIH HHS K07 CA218167
6 · The paper itself

Abstract

backgroundPatients with cancer frequently experience neuropsychiatric symptoms due to their medical illness or its treatment. In recent decades, psychiatrists have become increasingly involved in the care of patients with cancer. However, psychiatrists may be less familiar with hematopoietic stem cell transplantation (HSCT), a distinct cancer treatment modality associated with multiple neuropsychiatric sequelae.

objectiveTo provide an overview of HSCT, and describe the prevalence, impact, risk factors, and suggested management of psychiatric consequences of HSCT.

methodsWe performed literature searches in PubMed and PsychInfo to identify articles describing neuropsychiatric symptoms, including depression, anxiety, distress, post-traumatic stress disorder, delirium and cognitive impairment, resulting from HSCT in adults. Those articles most relevant to this manuscript were included.

resultsPsychiatrists may be involved in the treatment of patients before, during, or after inpatient hospitalization for HSCT. Each phase of treatment introduces unique stressors that may lead to or exacerbate psychiatric disorders. Appropriate management requires evaluation of HSCT-related medications, an understanding of the impact of complications from HSCT, and consideration of how the patient's underlying medical condition should influence psychiatric recommendations.

conclusionTo optimize patient outcomes, consulting psychiatrists should be familiar with the basic principles of HSCT, and the neuropsychiatric sequelae that may result from treatment. Further research is needed to identify strategies to manage psychiatric complications in this unique population.

Indexed as

AnxietyDepressionHematopoietic Stem Cell TransplantationHumansMental DisordersStress, Psychologicalbone marrow transplantationCancerhematopoietic stem cell transplantationneoplasmneuropsychiatryoncology

Identifiers

PMID30733043
PMCPMC6535361
OpenAlexW2909163881

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.